National Institute of Health (NIH)
National Institute on Aging (NIA)
Research Program Projects (P01)
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Gordon, M N; King, D L; Diamond, D M et al. (2001) Correlation between cognitive deficits and Abeta deposits in transgenic APP+PS1 mice. Neurobiol Aging 22:377-85
Arendash, G W; King, D L; Gordon, M N et al. (2001) Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes. Brain Res 891:42-53
Holcomb, L A; Gordon, M N; Jantzen, P et al. (1999) Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits. Behav Genet 29:177-85
Wright, K L; Morgan, D G; Yu, X et al. (1999) Mice transgenic for a human amyloid precursor protein promoter-lacZ reporter construct. J Mol Neurosci 13:111-20
Pennypacker, K R; Fuldner, R; Xu, R et al. (1998) Cloning and characterization of the presenilin-2 gene promoter. Brain Res Mol Brain Res 56:57-65
Benkovic, S A; McGowan, E M; Rothwell, N J et al. (1997) Regional and cellular localization of presenilin-2 RNA in rat and human brain. Exp Neurol 145:555-64
Gordon, M N; Schreier, W A; Ou, X et al. (1997) Exaggerated astrocyte reactivity after nigrostriatal deafferentation in the aged rat. J Comp Neurol 388:106-19