The Administrative Core will provide management services to each of the Projects and Cores in this Program. The Core will provide financial, adminstrative, and clerical services for the PI, the Co-Pi, Project Leaders, and Core Leaders for all grant-related activities. These activites include the preparation of this competing renewal, non-competing renewals including progress reports, preparation of budgets, communication with the NIH regarding renewals and all financial interactions, and assurance that the labs supported by this Program are in full compliance with all institutional, state and federal regulations. Core A will also coordinate and scheduling all meetings related to the function of the Program, including monthly meetings of all Project and Core Leaders, and members of their respective laboratories, as well as twice yearly meetings of the Internal and External Advisory Boards. Core A will also coordinate efforts with off-site investiators at the three neighboring institutions, Brigham and Women's Hospital, Beth Israel-Deaconess Hospital, and Children's Hospital of Boston, as well as interaction with the investigators at the DFCI. Dr. Gilliland is the PI and Director of this Core, and will serve as the overall scientific director and chief administrator. Dr. Griffin is the Co-Pi and will assist in these operations, particaulrly with regard to matters with the on-site investigators and clinical programs at the DFCI. He will assist Dr. Gilliland in monitoring protocol performance and will assist in protocol development. Alberto Jamarillo is a highly skilled administrator with experience in management of fiscal and administrative matters for large program project grants. He will serve as Administrative Facilitator, and coordinate Program administration and fiscal oversight with Dr. Gilliland and Dr. Griffin. Alberto Jamarillo will be assisted by Betsy Kelley, a Grants Management Specialist/Post Award, and Mariha Duarte, an administrative assistant, in coordination with Dr. Gilliland and Dr. Griffin, to manage budgets between participating institutions, prepare reports including noncompeting renewals, interface with the financial officers of each participating institution in the Program, and serve as an interface between these groups and the NIH. In addition, the Administrative Core will assure compliance with appropriate regulations regarding experimentation with human subjects, (including gender and minority participation) and vertebrate animals.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA066996-14
Application #
8254473
Study Section
Special Emphasis Panel (ZCA1)
Project Start
2011-04-01
Project End
2013-03-30
Budget Start
2011-04-01
Budget End
2012-03-31
Support Year
14
Fiscal Year
2011
Total Cost
$90,731
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
076580745
City
Boston
State
MA
Country
United States
Zip Code
02215
Wroblewski, Mark; Scheller-Wendorff, Marina; Udonta, Florian et al. (2018) BET-inhibition by JQ1 promotes proliferation and self-renewal capacity of hematopoietic stem cells. Haematologica 103:939-948
Konopleva, Marina; Letai, Anthony (2018) BCL-2 inhibition in AML: an unexpected bonus? Blood 132:1007-1012
Donovan, Katherine A; An, Jian; Nowak, Rados?aw P et al. (2018) Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome. Elife 7:
Lee, J Scott; Roberts, Andrew; Juarez, Dennis et al. (2018) Statins enhance efficacy of venetoclax in blood cancers. Sci Transl Med 10:
Liu, Bee Hui; Jobichen, Chacko; Chia, C S Brian et al. (2018) Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide. Proc Natl Acad Sci U S A 115:E7119-E7128
Kahn, Josephine D; Miller, Peter G; Silver, Alexander J et al. (2018) PPM1D-truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells. Blood 132:1095-1105
Libby, Peter; Ebert, Benjamin L (2018) CHIP (Clonal Hematopoiesis of Indeterminate Potential). Circulation 138:666-668
Wolach, Ofir; Sellar, Rob S; Martinod, Kimberly et al. (2018) Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms. Sci Transl Med 10:
Hogan, Louise E; K├Ârner, Christian; Hobbs, Kristen et al. (2018) NK-cell activation is associated with increased HIV transcriptional activity following allogeneic hematopoietic cell transplantation. Blood Adv 2:1412-1416
Kelly, Rachel S; Lasky-Su, Jessica; Yeung, Sai-Ching J et al. (2018) Integrative omics to detect bacteremia in patients with febrile neutropenia. PLoS One 13:e0197049

Showing the most recent 10 out of 376 publications