The Administrative Core A plays an essential role in administering, coordinating, and maintaining the integration and cohesion of this Program as the Project Leaders come from different departments of the Medical School. This Core supports the efforts of the Director, Dr. Chu, and Co-Director, Dr. Cheng, of the Core to oversee and direct the administration and management of this Program and to provide the scientific leadership that ensures the appropriate focus of the Project Leaders and essential scientific interactions. Moreover, this Core will ensure proper coordination of the individual Projects. This Core will provide the appropriate administrative services as well as financial oversight and management to support the Program and the individual Project Leaders. A major function supported by this Core is secretarial assistance to prepare progress reports, continuation reports, and renewals and to organize the Project Leaders monthly meetings. Once the External Advisory Board is constituted, this Core will organize the annual EAB meeting as well as organize the annual retreat. Thus, Core A is a critically important element to allow the Program to function as an efficient and cohesive unit. In addition, Core A will play a key role in ensuring the timely communication and dissemination of results in publications and highlight the progress of the research in various meetings and conferences.

Public Health Relevance

This is an interdepartmental, interdisciplinary multi-investigator grant comprised of 3 Projects designed to investigate the effect of a Chinese herbal medicine as a modulator of cancer chemotherapy. This Core provides administrative support to the P.L, Co-P.l., and Project Leaders to ensure proper coordination of the individual Projects and proper financial oversight.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Research Program Projects (P01)
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Special Emphasis Panel (ZCA1-GRB-S (M1))
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Yale University
New Haven
United States
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Tan, Hor-Yue; Wang, Ning; Lam, Wing et al. (2018) Targeting tumour microenvironment by tyrosine kinase inhibitor. Mol Cancer 17:43
Sun, Jiehuan; Herazo-Maya, Jose D; Huang, Xiu et al. (2018) Distance-correlation based gene set analysis in longitudinal studies. Stat Appl Genet Mol Biol 17:
Lam, Wing; Ren, Yongshen; Guan, Fulan et al. (2018) Mechanism Based Quality Control (MBQC) of Herbal Products: A Case Study YIV-906 (PHY906). Front Pharmacol 9:1324
Guan, Fulan; Lam, Wing; Hu, Rong et al. (2018) Majority of Chinese Medicine Herb Category ""Qing Re Yao"" Have Multiple Mechanisms of Anti-inflammatory Activity. Sci Rep 8:7416
Liu, Yiyi; Zhao, Hongyu (2017) Variable importance-weighted Random Forests. Quant Biol 5:338-351
Sun, Jiehuan; Herazo-Maya, Jose D; Kaminski, Naftali et al. (2017) A Dirichlet process mixture model for clustering longitudinal gene expression data. Stat Med 36:3495-3506
Lin, Zhixiang; Wang, Tao; Yang, Can et al. (2017) On joint estimation of Gaussian graphical models for spatial and temporal data. Biometrics 73:769-779
Sun, Jiehuan; Warren, Joshua L; Zhao, Hongyu (2017) A Bayesian semiparametric factor analysis model for subtype identification. Stat Appl Genet Mol Biol 16:145-158
Zhu, Ruoqing; Zhao, Ying-Qi; Chen, Guanhua et al. (2017) Greedy outcome weighted tree learning of optimal personalized treatment rules. Biometrics 73:391-400
Chao, Jung; Dai, Yuntao; Cheng, Hao-Yuan et al. (2017) Improving the Concentrations of the Active Components in the Herbal Tea Ingredient, Uraria crinita: The Effect of Post-harvest Oven-drying Processing. Sci Rep 7:38763

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