The Administrative Core coordinates the scheduling of meetings and research symposia involving the student and faculty participants and all planning arrangements. Regular meetings and correspondences occur between Program Project investigators at Vanderbilt University, OHSU, and the University of Minnesota. The purpose of these interactions is to evaluate ongoing research results that impact future directions and collaborations. At all three institutions there are numerous opportunities to exchange data. All program participants are trained in responsible conduct of research issues as offered at their respective institutions. The Core serves as the interface with the External Advisory Board (EAB) for the P01. The External Advisory Board is composed of internationally recognized scientists, who meet regularly with the PIs, evaluating progress and providing advice with regard to future research directions. Periodic meetings and correspondence will be held with the EAB to discuss scientific progress and future directions. The Administrative Core has the responsibility of working with all PPG-associated personnel with the following broad objectives: timely submission of Progress Reports, fiscal oversight and reporting for each of the projects and cores, The Core coordinates with the Vanderbilt University Office of Sponsored Research that directly communicates with off-site subcontracts at OHSU and University of Minnesota. A primary function will be to work with and assemble data and reports, including preparation of annual technical progress reports associated with this P01.

Public Health Relevance

The Administrative Core coordinates the operation and integration of the overall program, which is located at three sites?Vanderbilt University, Oregon Health & Science University, and the University of Minnesota. It coordinates communication and meetings between the three sites, and periodic meetings with members of the External Advisory Panel. It is responsible for preparing all annual reports. !

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA160032-28
Application #
9982803
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2020-08-01
Budget End
2021-07-31
Support Year
28
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Type
DUNS #
965717143
City
Nashville
State
TN
Country
United States
Zip Code
37203
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Patra, Amritraj; Su, Yan; Zhang, Qianqian et al. (2016) Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase ?. J Biol Chem 291:14134-45
Su, Yan; Egli, Martin; Guengerich, F Peter (2016) Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase ?. J Biol Chem 291:3747-56
Xu, Wenyan; Kool, Daniel; O'Flaherty, Derek K et al. (2016) O6-2'-Deoxyguanosine-butylene-O6-2'-deoxyguanosine DNA Interstrand Cross-Links Are Replication-Blocking and Mutagenic DNA Lesions. Chem Res Toxicol 29:1872-1882
Patra, Amitraj; Zhang, Qianqian; Guengerich, F Peter et al. (2016) Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase ?. J Biol Chem 291:24304-24313

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