Abstract

The Laboratory for Biomolecular Chemistry will provide analytic and synthetic services for program project investigators an assist in experimental design and data interpretation. These services include amino acid sequence and compositional analysis, HPLC separation of peptides, and custom synthesis of peptides and oligonucleotides.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
5P01DK033487-13
Application #
6105246
Study Section
Project Start
1999-01-01
Project End
1999-12-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
13
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Washington University
Department
Type
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Sukumar, N; Mathews, F S; Gordon, M M et al. (2009) Postcrystallization Analysis of the Irreproducibility of the Human Intrinsic Factor-Cobalamin Complex Crystals. Cryst Growth Des 9:348-351
Mathews, F S; Gordon, M M; Chen, Z et al. (2007) Crystal structure of human intrinsic factor: cobalamin complex at 2.6-A resolution. Proc Natl Acad Sci U S A 104:17311-6
Mahmood, Akhtar; Shao, Jian-su; Alpers, David H (2003) Rat enterocytes secrete SLPs containing alkaline phosphatase and cubilin in response to corn oil feeding. Am J Physiol Gastrointest Liver Physiol 285:G433-41
Shao, J; Sartor, R B; Dial, E et al. (2000) Expression of intrinsic factor in rat and murine gastric mucosal cell lineages is modified by inflammation. Am J Pathol 157:1197-205
Wen, J; Kinnear, M B; Richardson, M A et al. (2000) Functional expression in Pichia pastoris of human and rat intrinsic factor. Biochim Biophys Acta 1490:43-53
Brada, N; Gordon, M M; Shao, J S et al. (2000) Production of gastric intrinsic factor, transcobalamin, and haptocorrin in opossum kidney cells. Am J Physiol Renal Physiol 279:F1006-13
Zhou, Y; Kelly, D P; Strauss, A W et al. (1999) Characterization of the human very-long-chain acyl-CoA dehydrogenase gene promoter region: a role for activator protein 2. Mol Genet Metab 68:481-7
Syder, A J; Guruge, J L; Li, Q et al. (1999) Helicobacter pylori attaches to NeuAc alpha 2,3Gal beta 1,4 glycoconjugates produced in the stomach of transgenic mice lacking parietal cells. Mol Cell 3:263-74
Mathur, A; Sims, H F; Gopalakrishnan, D et al. (1999) Molecular heterogeneity in very-long-chain acyl-CoA dehydrogenase deficiency causing pediatric cardiomyopathy and sudden death. Circulation 99:1337-43
Li, Q; Karam, S M; Coerver, K A et al. (1998) Stimulation of activin receptor II signaling pathways inhibits differentiation of multiple gastric epithelial lineages. Mol Endocrinol 12:181-92

Showing the most recent 10 out of 81 publications