The objective of the Administrative Core is to coordinate the scientific efforts, provide cost-effective administrative and fiscal support, coordinate the activities of the Internal and External Advisory Committees, and interact with NICHD project staff regarding initiative for the program grant. All projects will utilize this Core equally. The Core Director, Dr. Bulun, has responsibilities for the day-to-day management of activities and direction of personnel (Figure 1). Priorities with respect to use of Core services will be determined in consultation with program faculty member under the guidance of PI, and the Co-PI and Internal Advisory Committee when necessary. Policies related to Core functions are reviewed and approved at monthly meetings of the project investigators.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
5P01HD057877-04
Application #
8382613
Study Section
Special Emphasis Panel (ZHD1-DSR-K)
Project Start
Project End
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
4
Fiscal Year
2012
Total Cost
$41,641
Indirect Cost
Name
Northwestern University at Chicago
Department
Type
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Park, Min Ju; Shen, Hailian; Spaeth, Jason M et al. (2018) Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19. J Biol Chem 293:4870-4882
Liu, Shimeng; Yin, Ping; Kujawa, Stacy A et al. (2018) Progesterone receptor integrates the effects of mutated MED12 and altered DNA methylation to stimulate RANKL expression and stem cell proliferation in uterine leiomyoma. Oncogene :
Griffin, Brannan B; Ban, Yanli; Lu, Xinyan et al. (2018) Hydropic leiomyoma: a distinct variant of leiomyoma closely related to HMGA2 overexpression. Hum Pathol :
Xu, Xiuhua; Kim, J Julie; Li, Yinuo et al. (2018) Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma. J Mol Med (Berl) 96:1095-1106
Zhang, Qing; Kanis, Margaux Jenna; Ubago, Julianne et al. (2018) The selected biomarker analysis in 5 types of uterine smooth muscle tumors. Hum Pathol 76:17-27
Zhang, Qing; Poropatich, Kate; Ubago, Julianne et al. (2018) Fumarate Hydratase Mutations and Alterations in Leiomyoma With Bizarre Nuclei. Int J Gynecol Pathol 37:421-430
Ikhena, Deborah E; Liu, Shimeng; Kujawa, Stacy et al. (2018) RANKL/RANK Pathway and Its Inhibitor RANK-Fc in Uterine Leiomyoma Growth. J Clin Endocrinol Metab 103:1842-1849
Ikhena, Deborah E; Bulun, Serdar E (2018) Literature Review on the Role of Uterine Fibroids in Endometrial Function. Reprod Sci 25:635-643
Vidimar, Vania; Chakravarti, Debabrata; Bulun, Serdar E et al. (2018) The AKT/BCL-2 Axis Mediates Survival of Uterine Leiomyoma in a Novel 3D Spheroid Model. Endocrinology 159:1453-1462
Xie, Jia; Xu, Xiuhua; Yin, Ping et al. (2018) Application of ex-vivo spheroid model system for the analysis of senescence and senolytic phenotypes in uterine leiomyoma. Lab Invest 98:1575-1587

Showing the most recent 10 out of 54 publications