The Administrative Core (Core C) coordinates the fiscal, scientific, and administrative aspects of the Program Project Grant (PPG). Dr. Joseph L. Goldstein will serve as the Director for the overall PPG. He has been the Director on this Program Project Grant since its beginning in 1977. Dr. Goldstein, who will be responsible for the PPG's overall scientific and financial matters, will be assisted in his administrative duties by Drs. Michael Brown and Jay Horton. Dr. Brown will be in charge of students and postdoctoral researchers. Dr. Horton will handle business matters concerning animals, human research protocols, and laboratory equipment. Drs. Horton and Goldstein will be assisted by a Financial Affairs Manager (Kay Pokladnik) who has worked on the PPG for 32 years; by an Administrative Coordinator (Mrs. Karen Schiller) who worked for 4 years as a Senior Grants and Contracts Specialist in the Office of Grants Management at UT Southwestern prior to working on this PPG for the last 7 years; and by a Laboratory Manager (Linda Donnelly), who has been associated with this PPG for 15 years. The Administrative Core will be responsible for personnel matters, for placing all purchase orders, for handling all protocols involving animals and human subjects, and for preparing weekly accounts of expenditures of each project for review by Drs. Horton and Goldstein. In addition to these administrative responsibilities, the Core will also be responsible for the typing and preparation of all our manuscripts, grant applications, and research progress reports. C/PPG 2015 ? Core C ? 30-line Summary

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
Project #
Application #
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Program Officer
Liu, Lijuan
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Texas Sw Medical Center Dallas
United States
Zip Code
Mitsche, Matthew A; Hobbs, Helen H; Cohen, Jonathan C (2018) Patatin-like phospholipase domain-containing protein 3 promotes transfer of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets. J Biol Chem 293:6958-6968
Banfi, Serena; Gusarova, Viktoria; Gromada, Jesper et al. (2018) Increased thermogenesis by a noncanonical pathway in ANGPTL3/8-deficient mice. Proc Natl Acad Sci U S A 115:E1249-E1258
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DeBose-Boyd, Russell A; Ye, Jin (2018) SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond. Trends Biochem Sci 43:358-368

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