Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
1P01HL046902-01
Application #
3844986
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Boston University
Department
Type
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Yang, Shenghong; Nugent, Matthew A; Panchenko, Mikhail P (2008) EGF antagonizes TGF-beta-induced tropoelastin expression in lung fibroblasts via stabilization of Smad corepressor TGIF. Am J Physiol Lung Cell Mol Physiol 295:L143-51
Kuang, Ping-Ping; Zhang, Xiao-Hui; Rich, Celeste B et al. (2007) Activation of elastin transcription by transforming growth factor-beta in human lung fibroblasts. Am J Physiol Lung Cell Mol Physiol 292:L944-52
Serlin, David M; Kuang, Ping Ping; Subramanian, Mangalalaxmy et al. (2006) Interleukin-1beta induces osteopontin expression in pulmonary fibroblasts. J Cell Biochem 97:519-29
Spencer, Jean L; Stone, Phillip J; Nugent, Matthew A (2006) New insights into the inhibition of human neutrophil elastase by heparin. Biochemistry 45:9104-20
Subramanian, Mangalalaxmy; Kuang, Ping-Ping; Wei, Lin et al. (2006) Modulation of amino acid uptake by TGF-beta in lung myofibroblasts. J Cell Biochem 99:71-8
Mitsi, Maria; Hong, Zhenning; Costello, Catherine E et al. (2006) Heparin-mediated conformational changes in fibronectin expose vascular endothelial growth factor binding sites. Biochemistry 45:10319-28
Kuang, Ping-Ping; Joyce-Brady, Martin; Zhang, Xiao-Hui et al. (2006) Fibulin-5 gene expression in human lung fibroblasts is regulated by TGF-beta and phosphatidylinositol 3-kinase activity. Am J Physiol Cell Physiol 291:C1412-21
Rishikof, David C; Lucey, Edgar C; Kuang, Ping-Ping et al. (2006) Induction of the myofibroblast phenotype following elastolytic injury to mouse lung. Histochem Cell Biol 125:527-34
DiCamillo, Sandra J; Yang, Shenghong; Panchenko, Maria V et al. (2006) Neutrophil elastase-initiated EGFR/MEK/ERK signaling counteracts stabilizing effect of autocrine TGF-beta on tropoelastin mRNA in lung fibroblasts. Am J Physiol Lung Cell Mol Physiol 291:L232-43
Kuang, Ping-Ping; Lucey, Edgar; Rishikof, David C et al. (2005) Engraftment of neonatal lung fibroblasts into the normal and elastase-injured lung. Am J Respir Cell Mol Biol 33:371-7

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