A.2 INTRODUCTION TO THE COREThis Core will continue to integrate the functions of a number of skilled personnel already present at theChildren's Hospital and University of Cincinnati College of Medicine. Core B will provide pathology/histologycollaboration for each investigator to determine any gross, microscopic and ultrastructural abnormalities ofthe mouse models and changes in gene expression. Murine cardiovascular physiology, both noninvasiveand invasive will also be provided. All of the Projects will use this core. The two Co-Directors, Dr. MelissaColbert and Dr. John Lorenz, are expert in the fields of murine cardiac histology/embryology and murinephysiology, respectively. Both have been involved in a number of important collaborations over the yearswith PPG personnel (see Introduction to the overall Program Project Grant). Dr. Colbert will lead thehistology/embryology facets of the Core while Dr. Lorenz will direct the physiology component.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
2P01HL069779-06A1
Application #
7429212
Study Section
Special Emphasis Panel (ZHL1-PPG-D (O2))
Project Start
2007-12-01
Project End
2012-11-30
Budget Start
2007-12-01
Budget End
2008-12-31
Support Year
6
Fiscal Year
2008
Total Cost
$447,147
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
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