Abstract

Public Health Relevance

Core A ? Administrative Core The Administrative Core will be headed by Dr. Rockman who serves as the overall Program Director of this PPG. An important aspect of this administrative component is assurance of the overall quality of research within the Program Project. While Dr. Rockman is the administrative PI, he is one of the Project Leaders who will equally share the responsibility of data quality control with the other Leaders of this PPG.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL075443-15
Application #
9698404
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Program Officer
Adhikari, Bishow B
Project Start
Project End
Budget Start
2019-06-01
Budget End
2020-05-31
Support Year
15
Fiscal Year
2019
Total Cost
Indirect Cost

  Institution

Name
Duke University
Department
Type
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705

  Publications

Zhou, Hua-Lin; Stomberski, Colin T; Stamler, Jonathan S (2018) Cross Talk Between S-Nitrosylation and Phosphorylation Involving Kinases and Nitrosylases. Circ Res 122:1485-1487
de Lucia, Claudio; Gambino, Giuseppina; Petraglia, Laura et al. (2018) Long-Term Caloric Restriction Improves Cardiac Function, Remodeling, Adrenergic Responsiveness, and Sympathetic Innervation in a Model of Postischemic Heart Failure. Circ Heart Fail 11:e004153
Grisanti, Laurel A; Schumacher, Sarah M; Tilley, Douglas G et al. (2018) Designer Approaches for G Protein-Coupled Receptor Modulation for Cardiovascular Disease. JACC Basic Transl Sci 3:550-562
de Lucia, Claudio; Eguchi, Akito; Koch, Walter J (2018) New Insights in Cardiac ?-Adrenergic Signaling During Heart Failure and Aging. Front Pharmacol 9:904
Wang, Jialu; Hanada, Kenji; Gareri, Clarice et al. (2018) Mechanoactivation of the angiotensin II type 1 receptor induces ?-arrestin-biased signaling through G?i coupling. J Cell Biochem 119:3586-3597
Hayashi, Hiroki; Hess, Douglas T; Zhang, Rongli et al. (2018) S-Nitrosylation of ?-Arrestins Biases Receptor Signaling and Confers Ligand Independence. Mol Cell 70:473-487.e6
Rizza, Salvatore; Cardaci, Simone; Montagna, Costanza et al. (2018) S-nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy. Proc Natl Acad Sci U S A 115:E3388-E3397
Cannavo, Alessandro; Koch, Walter J (2018) GRK2 as negative modulator of NO bioavailability: Implications for cardiovascular disease. Cell Signal 41:33-40
Wang, Jialu; Gareri, Clarice; Rockman, Howard A (2018) G-Protein-Coupled Receptors in Heart Disease. Circ Res 123:716-735
Kim, Jihee; Grotegut, Chad A; Wisler, James W et al. (2018) ?-arrestin 1 regulates ?2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility. Skelet Muscle 8:39

Showing the most recent 10 out of 167 publications