The Sleep Study and Recruitment Core is designed to provide important services to all three projects in the Program Project. The services provided are the following: 1. Subject Recruitment: The Core will provide an infrastructure with well-trained staff, cognizant of all issues about protection of subjects engaged in human research, who will take primary responsibility for recruitment of all subjects in the three projects of the Program Project. Performance of Sleep Studies: The Core will standardize the performance of sleep studies at the University of Pennsylvania and the University of Iceland, and conduct sleep studies at the University of Pennsylvania for all three projects. 3. Performance of More Complex Sleep Studies: The Core will provide skilled technologists for more complex procedures such as performance of Pcrit. 4. Review of Data: The Core will provide timely review (for quality and medical alerts) and scoring of all records and generate reports to be transferred to the Biostatical and Data Management Core (Core E). 5. Quality Assurance: The Core will conduct continuous quality assurance efforts for sleep studies to maintain high levels of technical performance of tests at the University of Pennsylvania and University of Iceland as well as scoring occurring in the Sleep Study Core Laboratory.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
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Heart, Lung, and Blood Initial Review Group (HLBP)
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University of Pennsylvania
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Keenan, Brendan T; Kim, Jinyoung; Singh, Bhajan et al. (2018) Recognizable clinical subtypes of obstructive sleep apnea across international sleep centers: a cluster analysis. Sleep 41:
van Hees, Vincent Theodoor; Sabia, S; Jones, S E et al. (2018) Estimating sleep parameters using an accelerometer without sleep diary. Sci Rep 8:12975
Shulman, Rachel; Cohen, Debbie L; Grandner, Michael A et al. (2018) Sleep duration and 24-hour ambulatory blood pressure in adults not on antihypertensive medications. J Clin Hypertens (Greenwich) 20:1712-1720
Feng, Yuan; Keenan, Brendan T; Wang, Stephen et al. (2018) Dynamic Upper Airway Imaging during Wakefulness in Obese Subjects with and without Sleep Apnea. Am J Respir Crit Care Med 198:1435-1443
Sands, Scott A; Edwards, Bradley A; Terrill, Philip I et al. (2018) Phenotyping Pharyngeal Pathophysiology using Polysomnography in Patients with Obstructive Sleep Apnea. Am J Respir Crit Care Med 197:1187-1197
Pien, Grace W; Ye, Lichuan; Keenan, Brendan T et al. (2018) Changing Faces of Obstructive Sleep Apnea: Treatment Effects by Cluster Designation in the Icelandic Sleep Apnea Cohort. Sleep 41:
Mazzotti, Diego R; Lim, Diane C; Sutherland, Kate et al. (2018) Opportunities for utilizing polysomnography signals to characterize obstructive sleep apnea subtypes and severity. Physiol Meas 39:09TR01
Sands, Scott A; Edwards, Bradley A; Terrill, Philip I et al. (2018) Identifying obstructive sleep apnoea patients responsive to supplemental oxygen therapy. Eur Respir J 52:
Gao, Xiaoling; Azarbarzin, Ali; Keenan, Brendan T et al. (2017) Heritability of Heart Rate Response to Arousals in Twins. Sleep 40:
Lyons, M Melanie; Keenan, Brendan T; Li, Junxin et al. (2017) Symptomless Multi-Variable Apnea Prediction Index Assesses Obstructive Sleep Apnea Risk and Adverse Outcomes in Elective Surgery. Sleep 40:

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