The administrative core is an essential component of our Program Project Grant. Dr. David Harrison, Principal Investigator, will meet either in person or by conference call with each project leader at least monthly on an individual basis. We also plan quarterly group meetings of all investigators via conference calls to review progress and to plan further research strategies, particularly emphasizing areas in which advances in one project may lead to the formulation of new hypotheses, or otherwise alter the conduct of studies in a different programmatic area. We also plan yearly meetings of the PPG investigators and at least two members of the external and internal advisory committees. Biostatistical support is a critical component of any research program. Dr. Yu Shyr, Professor and Chief, Division of Cancer Biostatistics, Department of Biostatistics, has served all components of this proposal as a consultant and collaborator and will continue this role throughout the duration of the program. Support for Dr. Shyr is therefore budgeted in this core. Investigators in this Program will be supported by the administrative services of this Core, particularly in preparation of non-competing renewals, in financial management, and in organization of the annual mini-site visits of the Advisory Committees. The administrative core will be responsible for coordinating the office management of the PPG. Ms. Berman, the Vanderbilt Grants Manager in Clinical Pharmacology and Ms. Amy Shelton, the Clinical Pharmacology business manager, will oversee all administrative aspects of the grant including progress report submission.
| Uribe, Jorge A; Aggarwal, Ishita; Witthayaweerasak, Juthamat et al. (2018) Refractory Giant Cell Arteritis Complicated by Vision Loss From Optic Atrophy and Maculopathy Associated With Pachymeningitis. J Neuroophthalmol 38:17-23 |
| Li, Yinyin; Goronzy, Jörg J; Weyand, Cornelia M (2018) DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system. Exp Gerontol 105:118-127 |
| Goronzy, Jörg J; Hu, Bin; Kim, Chulwoo et al. (2018) Epigenetics of T cell aging. J Leukoc Biol 104:691-699 |
| Weyand, Cornelia M; Berry, Gerald J; Goronzy, Jörg J (2018) The immunoinhibitory PD-1/PD-L1 pathway in inflammatory blood vessel disease. J Leukoc Biol 103:565-575 |
| Eriguchi, Masahiro; Bernstein, Ellen A; Veiras, Luciana C et al. (2018) The Absence of the ACE N-Domain Decreases Renal Inflammation and Facilitates Sodium Excretion during Diabetic Kidney Disease. J Am Soc Nephrol 29:2546-2561 |
| Watanabe, Ryu; Maeda, Toshihisa; Zhang, Hui et al. (2018) MMP (Matrix Metalloprotease)-9-Producing Monocytes Enable T Cells to Invade the Vessel Wall and Cause Vasculitis. Circ Res 123:700-715 |
| Weyand, Cornelia M; Shen, Yi; Goronzy, Jorg J (2018) Redox-sensitive signaling in inflammatory T cells and in autoimmune disease. Free Radic Biol Med 125:36-43 |
| Bernstein, Kenneth E; Khan, Zakir; Giani, Jorge F et al. (2018) Angiotensin-converting enzyme in innate and adaptive immunity. Nat Rev Nephrol 14:325-336 |
| Ye, Zhongde; Li, Guangjin; Kim, Chulwoo et al. (2018) Regulation of miR-181a expression in T cell aging. Nat Commun 9:3060 |
| Dikalov, Sergey I; Polienko, Yuliya F; Kirilyuk, Igor (2018) Electron Paramagnetic Resonance Measurements of Reactive Oxygen Species by Cyclic Hydroxylamine Spin Probes. Antioxid Redox Signal 28:1433-1443 |
Showing the most recent 10 out of 50 publications
