Initial Planning Stage Drs. Chung and Davidson have already identified an area of common interest and of high importance: the circadian biology of prostate cancer. Further, we have selected an Internal Advisory Committee made up of 6 distinguished cancer faculty, 3 from each partner institution to help select the 2nd and any future collaborative pilot projects that are to be funded via this grant. Consequently, the Planning Stage is virtually complete. For this reason we are only requesting 3 years of support, making this section unnecessary for our application. The only planning activities proposed are a series of lectures occurring both at MSM and WCI that are intended to help foster collaborations beyond those already proposed in this application. We will hold 4 lectures, 2 at MSM where Emory faculty involved in cancer research will be invited to speak about their research and meet with trainees. AUC faculty and students will be invited to the lectures. The other two will be presented by MSM cancer faculty at Emory. We will also host one major lecture per year at MSM on the topic of circadian biology of cancer. The speaker will be an internationally recognized cancer scientist or physician.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Exploratory Grants (P20)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Morehouse School of Medicine
United States
Zip Code
Ward, Tarsha; Wang, Ming; Liu, Xing et al. (2013) Regulation of a dynamic interaction between two microtubule-binding proteins, EB1 and TIP150, by the mitotic p300/CBP-associated factor (PCAF) orchestrates kinetochore microtubule plasticity and chromosome stability during mitosis. J Biol Chem 288:15771-85
Huang, Yuejia; Wang, Wenwen; Yao, Phil et al. (2012) CENP-E kinesin interacts with SKAP protein to orchestrate accurate chromosome segregation in mitosis. J Biol Chem 287:1500-9
Xia, Peng; Wang, Zhikai; Liu, Xing et al. (2012) EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis. Proc Natl Acad Sci U S A 109:16564-9
Wang, Xiwei; Zhuang, Xiaoxuan; Cao, Dan et al. (2012) Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules. J Biol Chem 287:39380-90
Yu, Xue; Wang, Fengsong; Liu, Hongsheng et al. (2011) ACAP4 protein cooperates with Grb2 protein to orchestrate epidermal growth factor-stimulated integrin ?1 recycling in cell migration. J Biol Chem 286:43735-47
Imanishi, Yorihisa; Hu, Bo; Xiao, Gutian et al. (2011) Angiopoietin-2, an angiogenic regulator, promotes initial growth and survival of breast cancer metastases to the lung through the integrin-linked kinase (ILK)-AKT-B cell lymphoma 2 (Bcl-2) pathway. J Biol Chem 286:29249-60
Evans, Jennifer A; Leise, Tanya L; Castanon-Cervantes, Oscar et al. (2011) Intrinsic regulation of spatiotemporal organization within the suprachiasmatic nucleus. PLoS One 6:e15869
Chu, Youjun; Yao, Phil Y; Wang, Wenwen et al. (2011) Aurora B kinase activation requires survivin priming phosphorylation by PLK1. J Mol Cell Biol 3:260-7
Zhang, Liangyu; Shao, Hengyi; Huang, Yuejia et al. (2011) PLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activity. J Biol Chem 286:3033-46
Yuan, Kai; Huang, Yuejia; Yao, Xuebiao (2011) Illumination of mitotic orchestra during cell division: a Polo view. Cell Signal 23:1-5

Showing the most recent 10 out of 18 publications