The Bioinformatics Core acts as a lynch pin in the overall success of the INBRE project by facilitating access to resources, knowhow, support and training to the INBRE network members in the use of computational resources and data analysis tools in bioinformatics. In simple terms, bioinformatics is a truly interdisciplinary field that attempts to solve biological questions using concepts from mathematics, statistics or computer science, which are implemented with the aid of computers. Bioinformatics has become an integral part of biological research due to the high-throughput nature of biological experiments (broadly dubbed as `omics' data). Thus, a tremendous need ensued for developing computational infrastructure for the collection, processing, storage, analysis and facilitating the use of such data by the research community. With parallel developments in computer science and high-throughput technologies in biology, biological data is being generated at a way faster pace than it can be analyzed and make sense out of. Moreover, the ever-changing technologies and data analysis tools make it more challenging to upkeep with the changing landscape of this field. Given the nature of this complexity, it is hard to expect from individual institutions to develop and maintain sophisticated infrastructure and technical expertise in bioinformatics. The primary goal of the INBRE program is to provide such environment, technology, tools and support accessible to all members of the INBRE network. The main objectives of the Bioinformatics Core include the development of needed infrastructure, provide tools and support for bioinformatic analyses, and train the INBRE scholars and investigators in the use of facilities and technologies.

Public Health Relevance

Research projects in the functional genomics area generate volumes of experimental data that could possibly be analyzed with the use of computers and bioinformatics tools. INBRE network institutions (especially PUIs) lack the infrastructure and technical knowhow to carryout bioinformatic analyses. The Core aims to develop the needed infrastructure and technical expertise and make it accessible to INBRE network institutions, provide technical support to independent research projects, and educate and train the INBRE scholars and researchers in the use of the resources developed by the Bioinformatics Core.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM103427-18
Application #
9719862
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2019-05-01
Budget End
2020-04-30
Support Year
18
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Nebraska Medical Center
Department
Type
DUNS #
168559177
City
Omaha
State
NE
Country
United States
Zip Code
68198
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