Alteration and Renovation Project

Horzempa, Joseph A.

Abstract

West Liberty University has a long history of participation with WV-INBRE, with four different investigators receiving major PUI research Awards and several faculty members receiving Faculty Research Development Awards. Recently West Liberty University began to develop a plan to renovate a portion of Arnett Hall, the building that houses the West Liberty University biology lecture and laboratory courses, in addition to the laboratories for biomedical research. This proposal outlines those plans to renovate a space that is nearly unusable (approximately 1200 sq. ft.) into a state-of-the-art research and teaching laboratory for Genetics, Molecular Biology, Biotechnology, and Immunology laboratory courses that will support our growing biomedical undergraduate and graduate programs. Moreover, we plan to install an animal suite in an existing portion of the building (approximately 180 sq. ft.) currently being used for storage. This will allow us to conduct infectious disease, immunology, and cancer research using rodent models. In August 2017, West Liberty University welcomed the inaugural class of our new graduate program in Biology. The animal research suite is absolutely essential for supporting graduate-level biomedical research that we hope to conduct at West Liberty University.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Exploratory Grants (P20)
• Project #: 2P20GM103434-19
• Application #: 9673947
• Study Section: Special Emphasis Panel (ZGM1)
• Budget Start: 2019-09-11
• Budget End: 2020-07-31
• Support Year: 19
• Fiscal Year: 2019

Institution

• Name: Marshall University
• DUNS #: 036156615
• City: Huntington
• State: WV
• Country: United States
• Zip Code: 25755

Publications

Nair, Rajesh R; Geldenhuys, Werner J; Piktel, Debbie et al. (2018) Novel compounds that target lipoprotein lipase and mediate growth arrest in acute lymphoblastic leukemia. Bioorg Med Chem Lett 28:1937-1942

Bohlen, Joseph; McLaughlin, Sarah L; Hazard-Jenkins, Hannah et al. (2018) Dysregulation of metabolic-associated pathways in muscle of breast cancer patients: preclinical evaluation of interleukin-15 targeting fatigue. J Cachexia Sarcopenia Muscle 9:701-714

Zdilla, Matthew J; Koons, Aaron W; Russell, Michelle L et al. (2018) The Infraorbital Foramen Is Located Midway Between the Nasospinale and Jugale: Considerations for Infraorbital Nerve Block and Maxillofacial Surgery. J Craniofac Surg 29:523-527

Zdilla, Matthew J; Skrzat, Janusz; Kozerska, Magdalena et al. (2018) Oval Window Size and Shape: a Micro-CT Anatomical Study With Considerations for Stapes Surgery. Otol Neurotol 39:558-564

Zhang, Shichao; Xing, Malcolm M Q; Li, Bingyun (2018) Capsule Integrated Polypeptide Multilayer Films for Effective pH-Responsive Multiple Drug Co-Delivery. ACS Appl Mater Interfaces :

Shepherd, Danielle L; Hathaway, Quincy A; Nichols, Cody E et al. (2018) Mitochondrial proteome disruption in the diabetic heart through targeted epigenetic regulation at the mitochondrial heat shock protein 70 (mtHsp70) nuclear locus. J Mol Cell Cardiol 119:104-115

Zhang, Yu; Chen, Shiguo; Wei, Chaoyang et al. (2018) Flavonoids from Chinese bayberry leaves induced apoptosis and G1 cell cycle arrest via Erk pathway in ovarian cancer cells. Eur J Med Chem 147:218-226

Han, Alice A; Currie, Holly N; Loos, Matthew S et al. (2018) The impact of cytokine responses in the intra- and extracellular signaling network of a traumatic injury. Cytokine 106:136-147

McAleer, Jeremy P; Fan, Jun; Roar, Bryanna et al. (2018) Cytokine Regulation in Human CD4 T Cells by the Aryl Hydrocarbon Receptor and Gq-Coupled Receptors. Sci Rep 8:10954

Zhang, Yu; Chen, Shiguo; Wei, Chaoyang et al. (2018) Dietary Compound Proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves inhibit angiogenesis and regulate cell cycle of cisplatin-resistant ovarian cancer cells via targeting Akt pathway. J Funct Foods 40:573-581