The proposed Center of Excellence on Diabetes in Americans of Mexican Descent aims to conductresearch on the physiologic progression to diabetes and its complications among Mexican Americans,and to develop diabetes prevention strategies and test innovative approaches to effective interventions ina minority population severely affected by type 2 diabetes. This Center proposes an administrative core, aresearch core including three research projects and two pilot studies, a training core and a communityengagement core.As part of the research core, the South Texas Parent Diabetes Prevention Trial (STPDPT) aims to test theeffectiveness of a brief motivational enhanced interview (MEI) treatment aimed at parents to modify thehome environment so that their children will: a) reduce 'screen time' or hours engaged in sedentarybehaviors; b) reduce consumption of high calorie, low nutrient foods; and c) increase levels of physicalactivity.
These aims will be accomplished by randomizing 360 children to one of two treatment conditions: a)the En Vivo! MEI telephone and Internet based parent treatment program; and b) no-treatment control. Wewill examine if positive changes in selected dietary, sedentary and physical activity behaviors result indecreased weight gain and risk factors associated with type 2 diabetes. The proposed project will impact: a)body mass index (BMI), b) C-reactive protein (CRP), c) insulin resistance, d) HbA1c, as well e) behavioraland psychosocial precursors to these physical measures. Families will be randomized to the STPDPTcondition or a comparison group; those in the treatment group will receive 6-9 MEI phone calls plus follow-upcontact via the Internet and newsletters and comic books over a 12 month period.
Study Aims : 1) To conductinterviews with parents, teachers, and students to determine overall feasibility of MEI telephone and Internetparent diabetes prevention strategies (Fall, 2007); 2) To conduct a cross sectional survey of 200 parents inthe South Texas Lower Rio Grande Valley to extend and confirm findings from Aim 1 (Spring, 2008); 3) Touse pilot data to tailor the MEI based parent program for parents (Summer 2008); 4) To assess the impactMEI based parent program on physiologic and behavioral outcomes on children aged 9-14 using randomizedclinical trial methodology with 360 families (parent/child dyad) recruited from members of the CameronCounty Hispanic Cohort (Fall 2008 - 2011).

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Exploratory Grants (P20)
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Special Emphasis Panel (ZRG1-DIG-B (52))
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University of Texas Health Science Center Houston
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