This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the Institutional Development Award (IDeA) Program is to foster health-related research and increase the competitiveness of investigators through support of faculty development and enhancement of the research infrastructure of institutions located in states with historically low aggregate success rates for grant awards from the NIH (RFA #RR-00-003). Thus, we have established a Center of Biomedical Research Excellence (COBRE), with the thematic focus of Functional Genomic/Proteomic Analysis of Bacterial-Host Interactions. The COBRE is headed by an established NIH-funded investigator and includes three new investigators and an established investigator who do not have a prior history of NIH R01 support. This is a state-wide initiative that includes the three major publicly-supported research institutions in the state of Oklahoma 1) the University of Oklahoma (OU), 2) the Oklahoma University Health Sciences Center (OUHSC), 3) Oklahoma State University (OSU) and the Oklahoma Medical Research Foundation (OMRF), a private research institute located near the OUHSC campus. The OUHSC functional genomics support core is equipped to perform all aspects of gene expression profiling using microarrays and high throughput DNA sequencing. The core also supports activities of the other COBRE cores, in particular the provision of high-throughput oligonucleotide synthesis, as needed. In addition, the core will spur faculty development by providing training and technical support to other OUHSC facult
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