This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is the administrative core for the COBRE grant at the University of Wyoming. The Administrative Core oversees the progress on the subprojects and involves the local IDeA Committee members and the External Advisory Committee members. Dr. Flynn organizes regular COBRE meetings, coordinates invited speaker seminars and committee meetings. A part time bookkeeper maintains records of expenditures and reports to Dr. Flynn. A component of the Administrative Core is Flynn's involvement with the university administration and working towards the goals of the COBRE. For example, through Flynn's efforts, Dr. Zhang, the Director of the microscopy facility, will assume a tenure-track position upon the end of the COBRE. Also, two new faculty were hired that will complement the COBRE. The budget of the Administrative Core contains funding of the Microscopy Facility and that of its Director, funding for DNA microarray studies, support for Pilot Projects, travel expenses for seminar speakers, grant writing workshops, and start-up for the second COBRE hire.

National Institute of Health (NIH)
National Center for Research Resources (NCRR)
Exploratory Grants (P20)
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Special Emphasis Panel (ZRR1-RI-8 (01))
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University of Wyoming
Schools of Arts and Sciences
United States
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Lu, Zhen; Marks, Eileen; Chen, Jianfang et al. (2014) Altered selenium status in Huntington's disease: neuroprotection by selenite in the N171-82Q mouse model. Neurobiol Dis 71:34-42
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Fox, Jonathan H; Connor, Teal; Stiles, Megan et al. (2011) Cysteine oxidation within N-terminal mutant huntingtin promotes oligomerization and delays clearance of soluble protein. J Biol Chem 286:18320-30
Green, Jade; Tyrrell, Zachary; Radosz, Maciej et al. (2011) Nanostructure of Solid Precipitates Obtained by Expansion of Polystyrene-block-Polybutadiene Solutions in Near Critical Propane: Block Ratio and Micellar Solution Effects. J Phys Chem C Nanomater Interfaces 115:9465-9470
Flynn, Francis W; Jensen, Dane D; Thakar, Amit et al. (2011) Neurokinin 3 receptor forms a complex with acetylated histone H3 and H4 in hypothalamic neurons following hyperosmotic challenge. Am J Physiol Regul Integr Comp Physiol 301:R822-31
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Taylor, W Andrew; Evans, Neil P; Hertz, Carole et al. (2011) Intra-pituitary administration revisited: development of a novel in vivo approach to investigate the ovine hypophysis. J Neurosci Methods 199:175-82
Jensen, D D; Sundstrom, K; Flynn, F W (2010) Expression of the nuclear transport protein importin ýý-1 and its association with the neurokinin 3 receptor in the rat hypothalamus following acute hyperosmotic challenge. Neuroscience 170:1020-7
Ye, Yi; Woodbury, C Jeffery (2010) Early postnatal loss of heat sensitivity among cutaneous myelinated nociceptors in Swiss-Webster mice. J Neurophysiol 103:1385-96

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