Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary goal of the Flow Cytometry Shared Resource (FCSR) is to assist investigators in acquiring experimental data which in turn will result in elucidation of mechanism of disease that will ultimately lead to better diagnostic tests and treatment of disease. FCSR scientific director works with investigators to develop specific biological questions, choose appropriate tools for inquiry, optimize available resources and result in meaningful analysis. The FCSR offers the following instruments: BD LSRII, BD FACS Calibur, BD FACS Aria, CompuCyte iCys laser scanning cytometer and Luminex 200 system. The core provides quality control and quality assurance for each instrument as well as cleaning and maintenance.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR016443-11
Application #
8168398
Study Section
Special Emphasis Panel (ZRR1-RI-8 (01))
Project Start
2010-07-01
Project End
2011-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
11
Fiscal Year
2010
Total Cost
$241,286
Indirect Cost

  Institution

Name
University of Kansas
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
016060860
City
Kansas City
State
KS
Country
United States
Zip Code
66160

  Publications

He, Chenchen; Duan, Shaofeng; Dong, Liang et al. (2017) Characterization of a novel p110?-specific inhibitor BL140 that overcomes MDV3100-resistance in castration-resistant prostate cancer cells. Prostate 77:1187-1198
Li, Jiaqin; Wehmeyer, Graham; Lovell, Scott et al. (2016) 1.65?Å resolution structure of the AraC-family transcriptional activator ToxT from Vibrio cholerae. Acta Crystallogr F Struct Biol Commun 72:726-31
Ponnurangam, Sivapriya; Dandawate, Prasad R; Dhar, Animesh et al. (2016) Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells. Oncotarget 7:3217-32
Freitas, Natalia; Lukash, Tetyana; Dudek, Megan et al. (2015) Capacity of a natural strain of woodchuck hepatitis virus, WHVNY, to induce acute infection in naive adult woodchucks. Virus Res 205:12-21
Kumaraswamy, E; Wendt, K L; Augustine, L A et al. (2015) BRCA1 regulation of epidermal growth factor receptor (EGFR) expression in human breast cancer cells involves microRNA-146a and is critical for its tumor suppressor function. Oncogene 34:4333-46
Grogan, Patrick T; Sarkaria, Jann N; Timmermann, Barbara N et al. (2014) Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation. Invest New Drugs 32:604-17
Freitas, Natalia; Abe, Kenji; Cunha, Celso et al. (2014) Support of the infectivity of hepatitis delta virus particles by the envelope proteins of different genotypes of hepatitis B virus. J Virol 88:6255-67
Tang, Yuzhe; Chen, Ruibao; Huang, Yan et al. (2014) Natural compound Alternol induces oxidative stress-dependent apoptotic cell death preferentially in prostate cancer cells. Mol Cancer Ther 13:1526-36
Freitas, Natalia; Cunha, Celso; Menne, Stephan et al. (2014) Envelope proteins derived from naturally integrated hepatitis B virus DNA support assembly and release of infectious hepatitis delta virus particles. J Virol 88:5742-54
Alhakamy, Nabil A; Nigatu, Adane S; Berkland, Cory J et al. (2013) Noncovalently associated cell-penetrating peptides for gene delivery applications. Ther Deliv 4:741-57

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