This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Introduction: The Administrative Core provides fiscal management and general oversight for the entire COBRE. Methods: The Core provides fiscal support for: mentors, all activities that promote scientific growth, new clinical and basic science junior faculty recruitment, and renovations. Results: The following are the results for year 1. The Core provided laboratory set-up monies for each COBRE JPI, opened accounts for each project and provided bi-monthly budget reports for each, coordinated hiring and the purchase of equipment and supplies for each project, coordinated all COBRE programs, initiated the major laboratory renovation plans, and provided the necessary documentation for a project by a new JPI project to take the spot of the JPI that graduated from the program after acquiring independent R01 funding for his project. The COBRE also received high marks from the first meeting of the External Advisory Committee (EAC). Discussion: The Center of Excellence in Oral and Craniofacial Biology has been greatly enhanced by the COBRE and has taken a large step toward enhancing the research enterprise at the LSU School of Dentistry with a critical mass of investigators, structured mentoring of promising junior investigators, and high quality oral health research.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR020160-03
Application #
7382150
Study Section
Special Emphasis Panel (ZRR1-RI-5 (02))
Project Start
2006-08-01
Project End
2007-07-31
Budget Start
2006-08-01
Budget End
2007-07-31
Support Year
3
Fiscal Year
2006
Total Cost
$452,612
Indirect Cost
Name
Louisiana State University Hsc New Orleans
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112
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Struckhoff, Amanda P; Rana, Manish K; Kher, Swapnil S et al. (2013) PDZ-RhoGEF is essential for CXCR4-driven breast tumor cell motility through spatial regulation of RhoA. J Cell Sci 126:4514-26
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Rana, Manish K; Worthylake, Rebecca A (2012) Novel mechanism for negatively regulating Rho-kinase (ROCK) signaling through Coronin1B protein in neuregulin 1 (NRG-1)-induced tumor cell motility. J Biol Chem 287:21836-45
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Kher, Swapnil S; Worthylake, Rebecca A (2011) Regulation of ROCKII membrane localization through its C-terminus. Exp Cell Res 317:2845-52
Fidel Jr, Paul L; Cutler, Jim E (2011) Prospects for development of a vaccine to prevent and control vaginal candidiasis. Curr Infect Dis Rep 13:102-7
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Lee, H; Yu, A; Johnson, C C et al. (2011) Fabrication of a multi-applicable removable intraoral denture system for rodent research. J Oral Rehabil 38:686-90

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