Abstract

Foster optimal balance and mobility and reduce injurious falls among older Americans. Our goals for this five year renewal award are to i. Promote multidisciplinary basic, translational and clinical inquiry into the causes, consequences and treatment of age related changes in balance and mobility, 2. Train young investigators from multiple disciplines within a vibrant intellectual and collaborative environment and 3) Serve as a resource and part:ner to other OAICs, investigators, institutions and the public. Our theme has evolved from a focus on balance and aging to one that better incorporates contemporary perspectives about the interface between balance and mobility, especially the role of control of motion during weight bearing activity. The OAIC has three Resource Cores (RCi- Clinical and Population Research Core, RC2- Tech Core and RC3- Data Management and Analysis Core) an RCDC, a PESC and an LAC. We propose four pilot studies and three developmental projects that reflect the scope and collaborative spirit of our program. The program integrates over 50 externally funded projects, funds three Pepper Scholars and provides support and training to over 20 additional young investigators who are funded through other sources of institutional and individual career awards

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
3P30AG024827-06S2
Application #
7938287
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8 (A1))
Program Officer
Hadley, Evan
Project Start
2004-09-30
Project End
2010-08-31
Budget Start
2009-09-30
Budget End
2010-08-31
Support Year
6
Fiscal Year
2009
Total Cost
$68,692
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Rejeski, W Jack; Walkup, Michael P; Fielding, Roger A et al. (2018) Evaluating Accelerometry Thresholds for Detecting Changes in Levels of Moderate Physical Activity and Resulting Major Mobility Disability. J Gerontol A Biol Sci Med Sci 73:660-667
Forman, Daniel E; Zieman, Susan J (2018) ""Doc, I Think My Meds Are Killing Me! Please Help…"": Transdisciplinary Forces Unite to Refocus Pharmacotherapy for Older Adults. J Am Geriatr Soc :
Lunney, June R; Albert, Steven M; Boudreau, Robert et al. (2018) Mobility Trajectories at the End of Life: Comparing Clinical Condition and Latent Class Approaches. J Am Geriatr Soc 66:503-508
Forman, Daniel E; Maurer, Mathew S; Boyd, Cynthia et al. (2018) Multimorbidity in Older Adults With Cardiovascular Disease. J Am Coll Cardiol 71:2149-2161
Gray, Shelly L; Hart, Laura A; Perera, Subashan et al. (2018) Meta-analysis of Interventions to Reduce Adverse Drug Reactions in Older Adults. J Am Geriatr Soc 66:282-288
Marcum, Zachary A; Forsberg, Christopher W; Moore, Kathryn P et al. (2018) Mortality Associated with Metformin Versus Sulfonylurea Initiation: A Cohort Study of Veterans with Diabetes and Chronic Kidney Disease. J Gen Intern Med 33:155-165
Kotlarczyk, Mary P; Perera, Subashan; Nace, David A et al. (2018) Identifying Sarcopenia in Female Long-Term Care Residents: A Comparison of Current Guidelines. J Am Geriatr Soc 66:316-320
Edmiston, Elizabeth; Dolansky, Mary A; Zullo, Melissa et al. (2018) Octogenarians' post-acute care use after cardiac valve surgery and recovery: clinical implications. Geriatr Nurs 39:371-375
Liu, Zuyun; Hsu, Fang-Chi; Trombetti, Andrea et al. (2018) Effect of 24-month physical activity on cognitive frailty and the role of inflammation: the LIFE randomized clinical trial. BMC Med 16:185
Smagula, Stephen F; Karim, Helmet T; Rangarajan, Anusha et al. (2018) Association of Hippocampal Substructure Resting-State Functional Connectivity with Memory Performance in Older Adults. Am J Geriatr Psychiatry 26:690-699

Showing the most recent 10 out of 1292 publications