The Biostatistics and Data Management Core (RC3) is one of four resource cores in the OAIC at the University of Florida. The mission ofthe UF OAIC is (1) to assess the risk factors and better understand the biological mechanisms of physical disability in older adults, (2) to develop and test effective prevention therapies, and (3) to educate and train new investigators in research on aging and disability, while developing their leadership qualities. The Biostatistics and Data Management Core is a key cog in the interaction between scientists from many disciplines to accomplish this mission. The core functions as both a data analysis resource and as a data coordinating center, involved in constructing data collection forms and managing the data (including quality control) for the studies conducted within the OAIC. In this capacity, the core maintains and updates the registry for the Recruitment, Adherence, and Retention Core (RC4) and tracks all research conducted within the OAIC with a web tracking system. The core is involved in all phases of these studies including initial study design and sample size calculations pre-proposal, randomization, and state-of-the-art statistical analyses once the data are completed. For study designs and data for which currently methodology is lacking, the core has the expertise to develop new state of the art methodology to perform correct and appropriate analyses of data collected in the Center. The Biostatistics and Data Management Core also is involved in preparation of manuscripts for dissemination within the research community. Finally, the Core serves as a key resource to the Junior Scholars of the Research Career Development Core (RCDC), providing consulting services and periodic special interest training topics, such as research methods, power analysis, analysis of incomplete data, principles of data management, and analysis of longitudinal data.
The core ensures proper and efficient designs and analyses for all studies conducted to examine sarcopenia and aging. In addition, the core provides the interface to the UF&Shands research data repository which can be invaluable for recruiting, generating research hypotheses, and pilot studies. The core also provides essential training for junior investigators and Pepper Scholars on research design and statistical methods and analyses.
|Wang, Kai; Cottler, Linda B (2018) Commentary on ""The association between sexual function and prostate cancer risk in US veterans"". Asian J Androl 20:99|
|Liu, Zuyun; Hsu, Fang-Chi; Trombetti, Andrea et al. (2018) Effect of 24-month physical activity on cognitive frailty and the role of inflammation: the LIFE randomized clinical trial. BMC Med 16:185|
|Davoudi, Anis; Corbett, Duane B; Ozrazgat-Baslanti, Tezcan et al. (2018) Activity and Circadian Rhythm of Sepsis Patients in the Intensive Care Unit. IEEE EMBS Int Conf Biomed Health Inform 2018:17-20|
|Hernandez, Caesar M; McQuail, Joseph A; Schwabe, Miranda R et al. (2018) Age-Related Declines in Prefrontal Cortical Expression of Metabotropic Glutamate Receptors that Support Working Memory. eNeuro 5:|
|Loftus, Tyler J; Efron, Philip A; Bala, Trina M et al. (2018) Hypertonic saline resuscitation after emergent laparotomy and temporary abdominal closure. J Trauma Acute Care Surg 84:350-357|
|Efron, Philip A; Mohr, Alicia M; Bihorac, Azra et al. (2018) Persistent inflammation, immunosuppression, and catabolism and the development of chronic critical illness after surgery. Surgery 164:178-184|
|Bea, Jennifer W; Wassertheil-Smoller, Sylvia; Wertheim, Betsy C et al. (2018) Associations between ACE-Inhibitors, Angiotensin Receptor Blockers, and Lean Body Mass in Community Dwelling Older Women. J Aging Res 2018:8491092|
|Mankowski, R T; Yende, S; Angus, D C (2018) Long-term impact of sepsis on cardiovascular health. Intensive Care Med :|
|Stortz, Julie A; Murphy, Tyler J; Raymond, Steven L et al. (2018) Evidence for Persistent Immune Suppression in Patients Who Develop Chronic Critical Illness After Sepsis. Shock 49:249-258|
|Kumar, Ashok; Foster, Thomas C (2018) Alteration in NMDA Receptor Mediated Glutamatergic Neurotransmission in the Hippocampus During Senescence. Neurochem Res :|
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