Administrative Core (Core A) The Administrative Core (Core A) provides the leadership, organizational structure, planning, educational opportunities and sound fiscal practices that propel CFAR investigators to achieve their highest scientific potential through innovative, multidisciplinary research collaborations that is at the heart of the UAB CFAR mission. The Administrative Core serves as the coordinating center for the entire UAB CFAR and is responsible for the continuous monitoring, evaluation, and assessment of service provision to assure full alignment with the strategic objectives of the Center. These critical functions are accomplished through high level engagement of the CFAR leadership in the activities of the Center, including: Frequent and effective communication with CFAR members, ongoing strategic planning, continuous monitoring of the effectiveness and outcomes of services and activities, assessment of scientific developments in the HIV research community, and alignment of existing scientific expertise and services at the UAB CFAR with these new developments and the NIH priorities. The core strives to enhance diversity within the Center and the development of early stage investigators to independence. Among the 45 new members recruited since the last renewal, 65% are women, 25% are under-represented / ethnic minorities. Of the new grants on the UAB funded research base this budget period, 38% were advanced with developmental pilot funding, demonstrating an ongoing commitment to fostering independence. Through participation in strategic recruitments, pilot funding and Interdisciplinary Research Groups (IRGs) / Scientific Working Groups (SWGs) the core enables critical management tools to foster new, dynamic programs aligned with emerging trends in HIV research. Since the last renewal, a cadre of 185 UAB HIV/AIDS investigators have been supported to work in a fully collaborative and effective fashion, achieving over $66M in total HIV funding to the institution and supporting over 1000 HIV publications. Leveraging a highly effectual administrative team, the core administrates several nationwide NIH-funded HIV program projects based at UAB (e.g., the CFAR Network of Integrated Clinical Systems (CNICS), the Creative and Novel Ideas in HIV Research (CNIHR), the HIV and Aging Pilot Program, the Women?s Interagency HIV Study?s joint site between UAB and the University of Mississippi Medical Center (WIHS), and the Alabama Clinical Trials Unit) recovering over $500,000 in salary support annually. Through these ongoing efforts, the Core will contribute new knowledge and approaches to curb HIV transmission, improve preventative, therapeutics and clinical outcomes, and have maximal impact on the global consequences of HIV.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI027767-32
Application #
9930520
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2020-06-01
Budget End
2021-05-31
Support Year
32
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Subramaniam, Akila; Van Der Pol, William J; Ptacek, Travis et al. (2018) Midtrimester microbial DNA variations in maternal serum of women who experience spontaneous preterm birth. J Matern Fetal Neonatal Med :1-9
Kay, Emma S; Rice, Whitney S; Crockett, Kaylee B et al. (2018) Experienced HIV-Related Stigma in Health Care and Community Settings: Mediated Associations With Psychosocial and Health Outcomes. J Acquir Immune Defic Syndr 77:257-263
Xu, Wanli; Luo, Zhenwu; Alekseyenko, Alexander V et al. (2018) Distinct systemic microbiome and microbial translocation are associated with plasma level of anti-CD4 autoantibody in HIV infection. Sci Rep 8:12863
Smith, Samuel R; Schaaf, Kaitlyn; Rajabalee, Nusrah et al. (2018) The phosphatase PPM1A controls monocyte-to-macrophage differentiation. Sci Rep 8:902
Wang, Yong; Schafer, Cara C; Hough, Kenneth P et al. (2018) Myeloid-Derived Suppressor Cells Impair B Cell Responses in Lung Cancer through IL-7 and STAT5. J Immunol 201:278-295
Jones, Robert B; Dorsett, Kaitlyn A; Hjelmeland, Anita B et al. (2018) The ST6Gal-I sialyltransferase protects tumor cells against hypoxia by enhancing HIF-1? signaling. J Biol Chem 293:5659-5667
Frugé, Andrew D; Van der Pol, William; Rogers, Laura Q et al. (2018) Fecal Akkermansia muciniphila Is Associated with Body Composition and Microbiota Diversity in Overweight and Obese Women with Breast Cancer Participating in a Presurgical Weight Loss Trial. J Acad Nutr Diet :
Dionne-Odom, Jodie; Westfall, Andrew O; Van Der Pol, Barbara et al. (2018) Sexually Transmitted Infection Prevalence in Women With HIV: Is There a Role for Targeted Screening? Sex Transm Dis 45:762-769
Howe, Chanelle J; Dulin-Keita, Akilah; Cole, Stephen R et al. (2018) Evaluating the Population Impact on Racial/Ethnic Disparities in HIV in Adulthood of Intervening on Specific Targets: A Conceptual and Methodological Framework. Am J Epidemiol 187:316-325
Crenshaw, Brennetta J; Gu, Linlin; Sims, Brian et al. (2018) Exosome Biogenesis and Biological Function in Response to Viral Infections. Open Virol J 12:134-148

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