Core N - The mission of the San Diego Center for AIDS Research (SD CFAR) Biostatistics and Modeling (BAM) Core is to provide quantitative expertise, collaboration, and training in the areas of biostatistics and infectious disease modeling related to HIV research. In accordance with NIH OAR priorities and our CFAR?s focus, we prioritize research in optimizing HIV care, alleviating HIV health disparities, and advancing discovery in HIV cure and vaccines. The BAM Core?s services are critical to our CFAR, as other quantitative shared resources across our institutions are generally not tailored to HIV research or focused on supporting emerging HIV investigators. Following a strategic planning process in 2016, the BAM Core was established in June 2016 as part of a restructuring of the Clinical Investigation (CI) Core and closure of the Bioinformatics and Information Technology (BIT) Core. Since its inception in June 2016, the BAM Core has provided support to 47 users (64% emerging), and 18 NIH-supported grants and supplements from 6 NIH institutes. In this short time, the BAM Core has been cited by 28 publications. The BAM Core is composed of two inter-connected units. The Biostatistics Unit handles statistical requests including pre-award statistical support and post-award collaboration. The Modeling Unit supports research involving HIV epidemic and pathogenesis modeling and health economic evaluation including pre-award support and post-award collaboration. Additionally, both units incorporate a particular focus on methodological innovation and training/mentoring in quantitative methods. The BAM Core aims are: (1) To support clinical investigation and translational HIV research by providing rigorous quantitative biostatistics support and services (Biostatistics Unit). (2) To enhance the impact of CFAR research by providing project guidance and high-level expertise on HIV infectious disease and economic modeling (Modeling Unit). (3) To encourage, mentor, and train the next generation of HIV investigators in biostatistics and modeling methodologies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI036214-24
Application #
9537797
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2018-04-01
Budget End
2019-03-31
Support Year
24
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of California, San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Chaillon, Antoine; Gianella, Sara; Lada, Steven M et al. (2018) Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc. J Virol 92:
Bengtson, Angela M; Pence, Brian W; Eaton, Ellen F et al. (2018) Patterns of efavirenz use as first-line antiretroviral therapy in the United States: 1999-2015. Antivir Ther 23:363-372
Dubé, Karine; Gianella, Sara; Concha-Garcia, Susan et al. (2018) Ethical considerations for HIV cure-related research at the end of life. BMC Med Ethics 19:83
Mittal, María Luisa; Bazzi, Angela Robertson; Rangel, María Gudelia et al. (2018) 'He's not my pimp': toward an understanding of intimate male partner involvement in female sex work at the Mexico-US border. Cult Health Sex 20:961-975
Letendre, Scott; Bharti, Ajay; Perez-Valero, Ignacio et al. (2018) Higher Anti-Cytomegalovirus Immunoglobulin G Concentrations Are Associated With Worse Neurocognitive Performance During Suppressive Antiretroviral Therapy. Clin Infect Dis 67:770-777
Basova, Liana; Najera, Julia A; Bortell, Nikki et al. (2018) Dopamine and its receptors play a role in the modulation of CCR5 expression in innate immune cells following exposure to Methamphetamine: Implications to HIV infection. PLoS One 13:e0199861
Eren, Kemal; Murrell, Ben (2018) RIFRAF: a frame-resolving consensus algorithm. Bioinformatics 34:3817-3824
de Almeida, Sérgio Monteiro; Ribeiro, Clea E; Rotta, Indianara et al. (2018) Biomarkers of neuronal injury and amyloid metabolism in the cerebrospinal fluid of patients infected with HIV-1 subtypes B and C. J Neurovirol 24:28-40
Martin, Thomas C S; Rauch, Andri; Salazar-Vizcaya, Luisa et al. (2018) Understanding and Addressing Hepatitis C Virus Reinfection Among Men Who Have Sex with Men. Infect Dis Clin North Am 32:395-405
Jenks, Jeffrey D; Hoenigl, Martin (2018) Treatment of Aspergillosis. J Fungi (Basel) 4:

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