Core N - The mission of the San Diego Center for AIDS Research (SD CFAR) Biostatistics and Modeling (BAM) Core is to provide quantitative expertise, collaboration, and training in the areas of biostatistics and infectious disease modeling related to HIV research. In accordance with NIH OAR priorities and our CFAR?s focus, we prioritize research in optimizing HIV care, alleviating HIV health disparities, and advancing discovery in HIV cure and vaccines. The BAM Core?s services are critical to our CFAR, as other quantitative shared resources across our institutions are generally not tailored to HIV research or focused on supporting emerging HIV investigators. Following a strategic planning process in 2016, the BAM Core was established in June 2016 as part of a restructuring of the Clinical Investigation (CI) Core and closure of the Bioinformatics and Information Technology (BIT) Core. Since its inception in June 2016, the BAM Core has provided support to 47 users (64% emerging), and 18 NIH-supported grants and supplements from 6 NIH institutes. In this short time, the BAM Core has been cited by 28 publications. The BAM Core is composed of two inter-connected units. The Biostatistics Unit handles statistical requests including pre-award statistical support and post-award collaboration. The Modeling Unit supports research involving HIV epidemic and pathogenesis modeling and health economic evaluation including pre-award support and post-award collaboration. Additionally, both units incorporate a particular focus on methodological innovation and training/mentoring in quantitative methods. The BAM Core aims are: (1) To support clinical investigation and translational HIV research by providing rigorous quantitative biostatistics support and services (Biostatistics Unit). (2) To enhance the impact of CFAR research by providing project guidance and high-level expertise on HIV infectious disease and economic modeling (Modeling Unit). (3) To encourage, mentor, and train the next generation of HIV investigators in biostatistics and modeling methodologies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI036214-25
Application #
9674224
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2019-04-01
Budget End
2020-03-31
Support Year
25
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of California, San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Garfein, Richard S; Liu, Lin; Cuevas-Mota, Jazmine et al. (2018) Tuberculosis Treatment Monitoring by Video Directly Observed Therapy in 5 Health Districts, California, USA. Emerg Infect Dis 24:1806-1815
Heldt, Sven; Prattes, Juergen; Eigl, Susanne et al. (2018) Diagnosis of invasive aspergillosis in hematological malignancy patients: Performance of cytokines, Asp LFD, and Aspergillus PCR in same day blood and bronchoalveolar lavage samples. J Infect 77:235-241
Jenks, Jeffrey Daniel; Hoenigl, Martin (2018) CD4:CD8 ratio and CD8+ cell count for prognosticating mortality in HIV-infected patients on antiretroviral therapy. J Lab Precis Med 3:
Canan, Chelsea E; Chander, Geetanjali; Monroe, Anne K et al. (2018) High-Risk Prescription Opioid Use Among People Living With HIV. J Acquir Immune Defic Syndr 78:283-290
Jiang, Wei; Luo, Zhenwu; Martin, Lisa et al. (2018) Drug Use is Associated with Anti-CD4 IgG-mediated CD4+ T Cell Death and Poor CD4+ T Cell Recovery in Viral-suppressive HIV-infected Individuals Under Antiretroviral Therapy. Curr HIV Res 16:143-150
White, Cory H; Beliakova-Bethell, Nadejda; Lada, Steven M et al. (2018) Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment. Front Immunol 9:603
Gianella, Sara; Marconi, Vincent C; Berzins, Baiba et al. (2018) Genital HIV-1 Shedding With Dolutegravir (DTG) Plus Lamivudine (3TC) Dual Therapy. J Acquir Immune Defic Syndr 79:e112-e114
Innes, Steve; Patel, Kunjal (2018) Noncommunicable diseases in adolescents with perinatally acquired HIV-1 infection in high-income and low-income settings. Curr Opin HIV AIDS 13:187-195
Morales, Mario; Rafful, Claudia; Gaines, Tommi L et al. (2018) Factors associated with extrajudicial arrest for syringe possession: results of a department-wide survey of municipal police in Tijuana, Mexico. BMC Int Health Hum Rights 18:36
Rhodes, Tim (2018) The becoming of methadone in Kenya: How an intervention's implementation constitutes recovery potential. Soc Sci Med 201:71-79

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