This is a revision of a new application to re-establish a Center for AIDS Research (CFAR) at the Johns Hopkins University (JHU). The new CFAR is comprised of more than 180 investigators from across all divisions of JHU and is based on a large portfolio of domestic and international HIV/AIDS research projects, with a Research Funding Base of $85 million for 165 grants to 136 Principal Investigators. This submission has been extensively revised on the basis of the critique of our 2010 application. We now propose six cores and three scientific working groups that will provide s a productive platform for promoting collaboration and synergy across the JHU HIV research community.
The aims ofthe JHU CFAR are to 1) Enhance integration and productivity of JHU HIV/AIDS research by promoting trans-disciplinary innovation and collaboration across disciplines and university divisions;2) Recruit new investigators into HIV/AIDS research to address the growing need for knowledge in rapidly emerging areas that affect the AIDS epidemic, e.g., co-infections, co-morbidities, substance abuse, and aging;3) Provide mentoring forth next generation of HIV/AIDS researchers and to recruit underrepresented minority investigators through mentoring and developmental grants;and 4) Mobilize the capacity of JHU to combat the HIV epidemic in Baltimore through engagement, training, outreach and community-based intervention studies.
These aims will be addressed across three broad themes: Development and Mentoring of New Investigators, Addressing the Baltimore HIV Epidemic, and Strengthening International Collaborations. We have garnered institutional commitments of $450,000 per year from the Provost and Deans of the medical, public health and nursing schools and $600,000 for leveraging recruitment of HIV investigators from Departments. This new CFAR represents a major commitment of investigators and institutional leadership to promote excellence, productivity and growth of HIV research and control efforts at JHU, in Baltimore and globally.

Public Health Relevance

HIV/AIDS is a major threat to global health and urban America. Research on HIV/AIDS has led to great improvements in the treatment and prevention of HIV disease, but much more needs to be done to control the epidemic. A CFAR will help coordinate, mobilize the substantial scientific, clinical and public health resources at JHU to generate new knowledge to understand, respond to, and control the HIV pandemic.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
1P30AI094189-01A1
Application #
8281943
Study Section
Special Emphasis Panel (ZAI1-RRS-A (J1))
Program Officer
Namkung, Ann S
Project Start
2012-05-02
Project End
2017-04-30
Budget Start
2012-05-02
Budget End
2013-04-30
Support Year
1
Fiscal Year
2012
Total Cost
$2,999,995
Indirect Cost
$1,148,146
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Smith, M Kumi; Graham, Matthew; Latkin, Carl A et al. (2018) Using Contact Patterns to Inform HIV Interventions in Persons Who Inject Drugs in Northern Vietnam. J Acquir Immune Defic Syndr 78:1-8
Canan, Chelsea E; Chander, Geetanjali; Monroe, Anne K et al. (2018) High-Risk Prescription Opioid Use Among People Living With HIV. J Acquir Immune Defic Syndr 78:283-290
Levinson, Kimberly L; Riedel, David J; Ojalvo, Laureen S et al. (2018) Gynecologic cancer in HIV-infected women: treatment and outcomes in a multi-institutional cohort. AIDS 32:171-177
Dean, Lorraine T; Nicholas, Lauren Hersch (2018) Using Credit Scores to Understand Predictors and Consequences of Disease. Am J Public Health 108:1503-1505
Mwinnyaa, George; Gray, Ronald H; Grabowski, Mary K et al. (2018) Brief Report: Age-Disparate Relationships and HIV Prevalence Among Never Married Women in Rakai, Uganda. J Acquir Immune Defic Syndr 79:430-434
Riddler, Sharon A; Zheng, Lu; Durand, Christine M et al. (2018) Randomized Clinical Trial to Assess the Impact of the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01 on HIV-1 Persistence in Individuals on Effective ART. Open Forum Infect Dis 5:ofy242
Grover, Surbhi; Desir, Fidel; Jing, Yuezhou et al. (2018) Reduced Cancer Survival Among Adults With HIV and AIDS-Defining Illnesses Despite No Difference in Cancer Stage at Diagnosis. J Acquir Immune Defic Syndr 79:421-429
Sturgeon, Kathleen M; Hackley, Renata; Fornash, Anna et al. (2018) Strategic recruitment of an ethnically diverse cohort of overweight survivors of breast cancer with lymphedema. Cancer 124:95-104
Page, Kathleen R; Grieb, Suzanne Dolwick; Nieves-Lugo, Karen et al. (2018) Enhanced immigration enforcement in the USA and the transnational continuity of HIV care for Latin American immigrants in deportation proceedings. Lancet HIV 5:e597-e604
Sengupta, Srona; Siliciano, Robert F (2018) Targeting the Latent Reservoir for HIV-1. Immunity 48:872-895

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