The purpose of the Sidney Kimmel Comprehensive Cancer Center (SKCCC) Cancer Functional Imaging Core (CFIC) is to integrate state-of-the-art noninvasive imaging capabilities to advance the translational research mission of SKCCC members. Within the past five, years the Core has significantly expanded to include an Olympus multiphoton microscope for in vivo imaging, a LI-COR Pearl imager, a SuperArgus PET/CT scanner and a Vector SPECT/PET scanner. These are in addition to the existing 9.4T Bruker horizontal bore MR scanner, Kodak and Xenogen optical imaging systems, a Gamma-Medica CT/SPECT and an Argus PET imaging system, and a VisualSonics ultrasound imaging system. The equipment is housed in a 2,400 ft2 small- animal imaging facility in Miller Research Building (MRB), overseen by dedicated technical staff members. These Cancer Functional Imaging Core facilities provide SKCCC members with advanced small-animal imaging capabilities that result in high-impact peer-reviewed publications and research funding. These imaging techniques are translatable into the clinic, providing imaging data in small animals used to develop translational applications in humans. Zaver M. Bhujwalla, Ph.D., is the Director of the Cancer Functional Imaging Core. She is also Program Co- Leader of the SKCCC Cancer Molecular and Functional Imaging Program and the Director of the Johns Hopkins University ICMIC (In Vivo Cellular Molecular Imaging Center) Program. Dr. Bhujwalla directs a newly created Division of Cancer Imaging Research in the Department of Radiology and Radiological Science. Dr. Bhujwalla has an outstanding track record in molecular imaging applications in cancer. The two Associate Directors, Martin G. Pomper, M.D., Ph.D., and Dmitri Artemov, Ph.D., are well-known investigators who played a key role in the establishment of molecular imaging at The Johns Hopkins University (JHU). Dr. Pomper directs the Division of Nuclear Medicine and Molecular Imaging. He is also Co-Leader of the SKCCC Cancer Molecular and Functional Imaging Program and Associate Director of the JHU ICMIC. SKCCC Managed Core Reporting Period: Jan. 1, 2015, to Dec. 31, 2015

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA006973-55
Application #
9519873
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2018-05-01
Budget End
2019-04-30
Support Year
55
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Palsgrove, Doreen N; Brosnan-Cashman, Jacqueline A; Giannini, Caterina et al. (2018) Subependymal giant cell astrocytoma-like astrocytoma: a neoplasm with a distinct phenotype and frequent neurofibromatosis type-1-association. Mod Pathol 31:1787-1800
Adler, B L; Pezhouh, M K; Kim, A et al. (2018) Histopathological and immunophenotypic features of ipilimumab-associated colitis compared to ulcerative colitis. J Intern Med 283:568-577
Anchoori, Ravi K; Jiang, Rosie; Peng, Shiwen et al. (2018) Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer. ACS Omega 3:11917-11929
Shanbhag, Satish; Ambinder, Richard F (2018) Hodgkin lymphoma: A review and update on recent progress. CA Cancer J Clin 68:116-132
Forde, Patrick M; Chaft, Jamie E; Smith, Kellie N et al. (2018) Neoadjuvant PD-1 Blockade in Resectable Lung Cancer. N Engl J Med 378:1976-1986
Cottrell, Tricia R; Duong, Anh T; Gocke, Christopher D et al. (2018) PD-L1 expression in inflammatory myofibroblastic tumors. Mod Pathol 31:1155-1163
Kelley, Dylan Z; Flam, Emily L; Guo, Theresa et al. (2018) Functional characterization of alternatively spliced GSN in head and neck squamous cell carcinoma. Transl Res 202:109-119
Knapp, Emily A; Dean, Lorraine T (2018) Consumer credit scores as a novel tool for identifying health in urban U.S. neighborhoods. Ann Epidemiol 28:724-729
Tolbert, Elliott; Brundage, Michael; Bantug, Elissa et al. (2018) Picture This: Presenting Longitudinal Patient-Reported Outcome Research Study Results to Patients. Med Decis Making 38:994-1005
Paller, Channing J; Zhou, Xian C; Heath, Elisabeth I et al. (2018) Muscadine Grape Skin Extract (MPX) in Men with Biochemically Recurrent Prostate Cancer: A Randomized, Multicenter, Placebo-Controlled Clinical Trial. Clin Cancer Res 24:306-315

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