Abstract

The Wistar Institute Cancer Center Director is Dr. Russel Kaufman. He is assisted by two Deputy Directors: Drs. Meenhard Herlyn and Frank J. Rauscher, III. Dr. Herlyn is the Deputy Director for Translational Research. In this newly created position, Dr. Herlyn will cultivate intra- and inter-programmatic translational collaborations within the Cancer Center, helping to ensure that the needs of the Cancer Center principal investigators are met. He also will share in the recruiting efforts for new members of the Cancer Center, and provide advice to the Director. Dr. Frank J. Rauscher III is the Deputy Director for Basic Research. He holds several important national positions that give him a perspective on the directions and opportunities in basic cancer research, enabling him to provide scientific guidance to the Cancer Center Director and take a leadership role with program leaders and Cancer Center members in basic research planning, recruitment, and development of infrastructure.

Public Health Relevance

Three very experienced cancer scientists and administrators with extensive national leadership experience head the Cancer Center, providing vision, perspective, and creative energy that will enhance the collaborations and effectiveness of the Cancer Center and make it an exciting, innovative environment for beginning scientists to start their careers.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA010815-40
Application #
7944993
Study Section
Subcommittee G - Education (NCI)
Project Start
2009-04-15
Project End
2014-02-28
Budget Start
2009-04-15
Budget End
2010-02-28
Support Year
40
Fiscal Year
2009
Total Cost
$280,753
Indirect Cost

  Institution

Name
Wistar Institute
Department
Type
DUNS #
075524595
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Li, Heng; Wang, Zhize; Xiao, Wei et al. (2018) Androgen-receptor splice variant-7-positive prostate cancer: a novel molecular subtype with markedly worse androgen-deprivation therapy outcomes in newly diagnosed patients. Mod Pathol 31:198-208
Shastrula, Prashanth K; Rice, Cory T; Wang, Zhuo et al. (2018) Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes. Nucleic Acids Res 46:972-984
Duperret, Elizabeth K; Trautz, Aspen; Ammons, Dylan et al. (2018) Alteration of the Tumor Stroma Using a Consensus DNA Vaccine Targeting Fibroblast Activation Protein (FAP) Synergizes with Antitumor Vaccine Therapy in Mice. Clin Cancer Res 24:1190-1201
Heppt, Markus V; Wang, Joshua X; Hristova, Denitsa M et al. (2018) MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression. J Invest Dermatol 138:141-149
Wu, Shuai; Fatkhutdinov, Nail; Fukumoto, Takeshi et al. (2018) SWI/SNF catalytic subunits' switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells. Nat Commun 9:4116
Ecker, Brett L; Kaur, Amanpreet; Douglass, Stephen M et al. (2018) Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis. Cancer Discov :
Abdel-Mohsen, Mohamed; Kuri-Cervantes, Leticia; Grau-Exposito, Judith et al. (2018) CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells. Sci Transl Med 10:
Fukumoto, Takeshi; Magno, Elizabeth; Zhang, Rugang (2018) SWI/SNF Complexes in Ovarian Cancer: Mechanistic Insights and Therapeutic Implications. Mol Cancer Res 16:1819-1825
Cañadas, Israel; Thummalapalli, Rohit; Kim, Jong Wook et al. (2018) Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses. Nat Med 24:1143-1150
Basu, Subhasree; Gnanapradeepan, Keerthana; Barnoud, Thibaut et al. (2018) Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1?. Genes Dev 32:230-243

Showing the most recent 10 out of 741 publications