The Developmental Funds of the CCSG represent one of the most important components of the Core grant in that they allow the Center director to respond to and provide leadership for the scientific needs and priorities of the Center. We use these funds in several ways. First, """"""""New Investigator"""""""" funds are used together with other Center funds (e.g., gift account) and funds from departments and other Centers to provide attractive recruitment packages for faculty important to the Cancer Center's research enterprise. These recruitments may represent a build-up for a new research initiative or expansion of an existing program or replacement for departing or retiring faculty. We have asked for an increase in this category from $300,000/year to $400,000/year reflecting the increasing costs of recruitment and the excellent """"""""return"""""""" in terms of leadership and grant support by recipients. The second use of these funds is for our """"""""pilot"""""""" grant program which utilizes a University-wide application process with an emphasis on young or new faculty. We fully fund 3 pilot grants annually ($40,000 each) and contribute to 3 other (Core grant - $10,000 and ACS institutional grant - $20,000) in 2 separate annual competitions. Our Scientific Advisory Committee reviews and critiques these applications for Cancer Center research priorities and potential for national funding. The recipients of these funds have an excellent track record of successful grant funding (annual direct of $3.9 million and over $11 million for recipients of the past 4 years) and scientific growth of our programs. In addition to the above, we also have a strategy of funding new developmental shared facilities using developmental funds or Core grant re-budgeting to the developmental fund category. This funding period we funded 3 developmental shared facilities (Small Animal Imaging;DNA Sequencing;and Molecular Biology/Recombinant Protein) using funds re-budgeted from the Shared Facility category as well as initiating our Gene Expression facility out of the gift account (equipment and start-up personnel).

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Alabama Birmingham
United States
Zip Code
Buford, Thomas W; Carter, Christy S; VanDerPol, William J et al. (2018) Composition and richness of the serum microbiome differ by age and link to systemic inflammation. Geroscience 40:257-268
Kim, Harrison (2018) Variability in Quantitative DCE-MRI: Sources and Solutions. J Nat Sci 4:
Pruitt, Hawley C; Metge, Brandon J; Weeks, Shannon E et al. (2018) Conditional knockout of N-Myc and STAT interactor disrupts normal mammary development and enhances metastatic ability of mammary tumors. Oncogene 37:1610-1623
Frugé, Andrew D; Van der Pol, William; Rogers, Laura Q et al. (2018) Fecal Akkermansia muciniphila Is Associated with Body Composition and Microbiota Diversity in Overweight and Obese Women with Breast Cancer Participating in a Presurgical Weight Loss Trial. J Acad Nutr Diet :
Jo, SeongHo; Chen, Junqin; Xu, Guanlan et al. (2018) miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function. Diabetes 67:256-264
Boitano, Teresa K L; Smith, Haller J; Rushton, Tullia et al. (2018) Impact of enhanced recovery after surgery (ERAS) protocol on gastrointestinal function in gynecologic oncology patients undergoing laparotomy. Gynecol Oncol 151:282-286
Frugé, Andrew D; Ptacek, Travis; Tsuruta, Yuko et al. (2018) Dietary Changes Impact the Gut Microbe Composition in Overweight and Obese Men with Prostate Cancer Undergoing Radical Prostatectomy. J Acad Nutr Diet 118:714-723.e1
Crenshaw, Brennetta J; Gu, Linlin; Sims, Brian et al. (2018) Exosome Biogenesis and Biological Function in Response to Viral Infections. Open Virol J 12:134-148
Si, Ying; Cui, Xianqin; Crossman, David K et al. (2018) Muscle microRNA signatures as biomarkers of disease progression in amyotrophic lateral sclerosis. Neurobiol Dis 114:85-94
Sahay, Bikash; Bashant, Kathleen; Nelson, Nicole L J et al. (2018) Induction of Interleukin 10 by Borrelia burgdorferi Is Regulated by the Action of CD14-Dependent p38 Mitogen-Activated Protein Kinase and cAMP-Mediated Chromatin Remodeling. Infect Immun 86:

Showing the most recent 10 out of 747 publications