The University of Chicago Cancer Research Center (UCCRC) is a formal academic unit with departmental status within the Division of the Biological Sciences (BSD). The Director has department chair status and sits on the Division's governing bodies. The Director has control over administrative and research space, fiscal responsibility for the CCSG, American Cancer Society Institutional Research Grant (ACS-IRG), caBIG contract with NCI, philanthropic funds raised by the University of Chicago Cancer Research Foundation (UCCRF), and interdepartmental/interdisciplinary grants >$500,000 annual direct costs. The Director has authority over UCCRC membership and appointments, direct and shared authority over shared resources, and full authority over UCCRC philanthropic activities. Under the leadership of Dr. Marcy List, Associate Director for Administration, the UCCRC is responsible for managing all of these activities as they relate to both the administrative needs of the UCCRC, and the research operations of the 198 UCCRC investigators. The UCCRC administrative unit is subdivided into seven subunits: Finances and Human Resources*, Informatics, Grant and Program Development, Clinical TrialsA, Fundraising*, Communications*, and the Cancer Resource Center* (* indicates no CCSG funds requested;A described in Section 9.1.13). The Financial Unit (Director for Finance plus 2 additional FTE's) is responsible for all pre- and post-award activities for over $5.5 million (annual direct costs) in federal and non-federal grants and contracts, and $9.3 million in philanthropic funds, and the allocation of UCCRC funds through RFA's. At present, the office manages a SPORE grant, a Leukemia and Lymphoma Society SCOR, the CCSG, the ACS-IRG, caBIG contract, and numerous foundation accounts. The Informatics Unit (Director for Informatics plus 5 additional FTE's) is responsible for all informatics and database support for UCCRC administrative units, the CCTO and UCCRC investigators as well as coordinating UCCRC IT activities with those of the BSD and University of Chicago Medical Center, and supporting the UCCRC Website. Four FTE's are responsible for Grant and Program Development Support, which includes all non-financial pre- and post-award support for large cancer-related grants (in the past 3 years, this group has been responsible for the submission of the CCSG, ACS-IRG, 4 SPORE applications, 2 SCOR applications, and 1 Tumor Microenvironment Network application);coordination of program and overall UCCRC development, planning and evaluation activities; and coordination of activities related to membership and recruitment. These activities represent a significant expansion of UCCRC responsibilities, with a parallel increase in staff.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Chicago
United States
Zip Code
Lee, Ji-Hye; Park, Beom Seok; Han, Kang R et al. (2018) Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication. Front Microbiol 9:1466
Cheng, Jason X; Chen, Li; Li, Yuan et al. (2018) RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nat Commun 9:1163
Johnson, Marianna B; Hoffmann, Joscelyn N; You, Hannah M et al. (2018) Psychosocial Stress Exposure Disrupts Mammary Gland Development. J Mammary Gland Biol Neoplasia 23:59-73
Sweis, Randy F; Zha, Yuanyuan; Pass, Lomax et al. (2018) Pseudoprogression manifesting as recurrent ascites with anti-PD-1 immunotherapy in urothelial bladder cancer. J Immunother Cancer 6:24
Kathayat, Rahul S; Cao, Yang; Elvira, Pablo D et al. (2018) Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes. Nat Commun 9:334
Liu, Jun; Eckert, Mark A; Harada, Bryan T et al. (2018) m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol 20:1074-1083
Bhanvadia, Raj R; VanOpstall, Calvin; Brechka, Hannah et al. (2018) MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease. Clin Cancer Res 24:3668-3680
Wood, Kevin; Byron, Elizabeth; Janisch, Linda et al. (2018) Capecitabine and Celecoxib as a Promising Therapy for Thymic Neoplasms. Am J Clin Oncol 41:963-966
Sample, Ashley; Zhao, Baozhong; Wu, Chunli et al. (2018) The Autophagy Receptor Adaptor p62 is Up-regulated by UVA Radiation in Melanocytes and in Melanoma Cells. Photochem Photobiol 94:432-437
Hrusch, C L; Manns, S T; Bryazka, D et al. (2018) ICOS protects against mortality from acute lung injury through activation of IL-5+ ILC2s. Mucosal Immunol 11:61-70

Showing the most recent 10 out of 668 publications