The objective of the Bioinformatics Shared Resource (BISR) is to support the application of advanced computational and bioinformatics resources for cancer research conducted by NCCC investigators. The BISR will provide the infrastructure and consultation necessary for the use of computational tools and informatics databases in innovative ways. Specifically, the BISR has as its goals: 1. the advancement of bioinformatics and molecular biological information infrastructure; 2. the provision of leading-edge computational resources to enable solutions to important problems in molecular biology; 3. the education of researchers in bioinformatics; and 4. the assistance of researchers in the exploitation of high performance computing. The BISR is managed by a faculty director, Dr. C. Robertson McClung, and is overseen by an Internal Advisory Committee. The BISR is staffed by three consultants; two doctoral level and one masters level. The Resource staff are available for consultation on experimental design and data analysis. The BISR, in collaboration with Dartmouth Academic Computing, supports an extensive set of software applications that comprehensively address the needs of NCCC investigators in the analysis of organism-scale datasets in the areas of DNA sequence (genome), gene expression (transcriptome), protein expression (proteome), protein structural analysis (with an emphasis on NMR and crystallographic techniques), and small molecules (metabolome). This Resource also collaborates with the Molecular Biology & Proteomics Shared Service and the Microarray Shared Resource in providing seamless support for the investigator who is applying these tools to their research. The addition of these new resources is expected to significantly increase the user base of NCCC investigators.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA023108-26
Application #
6989423
Study Section
Subcommittee G - Education (NCI)
Project Start
2004-07-02
Project End
2008-11-30
Budget Start
2004-07-02
Budget End
2004-11-30
Support Year
26
Fiscal Year
2004
Total Cost
$22,251
Indirect Cost
Name
Dartmouth College
Department
Type
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
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