The program leaders and co-leaders of the Purdue University Center for Cancer Research includes Drs. Elizabeth Taparowsky and David Riese function as leader and co-leader, respectively, of the Cell Growth and Differentiation Program. Drs. Cynthia Stauffacher and David Thompson are leader and co-leader, respectively, of the Chemical and Structural Biology Program. Drs. Richard Gibbs and Deborah Knapp are leader and co-leader of the Medicinal Chemistry Program and Drs Donald Bergstrom and Alex Wei are leader and co-leader of the Drug Delivery and Molecular Sensing Program. These leaders have distinguished and highly collaborative research laboratories and have functioned to guide their respective programs. They organize programmatic meetings, set goals, mentor members and encourage transdisciplinary participation in research efforts. Further, all serve on the primary decision making body of the Center, the Executive Committee. In this capacity all provide input on major decision of the Center and thus, contribute to determining the future mission of the Center.

Public Health Relevance

The program leaders and co-leaders provide vision, resources and organizational capacity for the Center that enables the pursuit of collaborative research. The collaborative efforts bring together scientists from many disciplines to address cancer-related problems. Throught these transdisciplinary investigations, novel discoveries are made that lead to improvement in early detection and care of cancer patients.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023168-31
Application #
8303458
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
31
Fiscal Year
2011
Total Cost
$19,895
Indirect Cost
Name
Purdue University
Department
Type
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907
Lee, Hyeon Jeong; Li, Jie; Vickman, Renee E et al. (2018) Cholesterol Esterification Inhibition Suppresses Prostate Cancer Metastasis by Impairing the Wnt/?-catenin Pathway. Mol Cancer Res 16:974-985
Bhandari, Pushpak; Novikova, Gloriia; Goergen, Craig J et al. (2018) Ultrasound beam steering of oxygen nanobubbles for enhanced bladder cancer therapy. Sci Rep 8:3112
Dhawan, Deepika; Hahn, Noah M; Ramos-Vara, José A et al. (2018) Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer. PLoS Genet 14:e1007571
Shinde, Aparna; Libring, Sarah; Alpsoy, Aktan et al. (2018) Autocrine Fibronectin Inhibits Breast Cancer Metastasis. Mol Cancer Res 16:1579-1589
Ghosh, Arun K; Ghosh, Koena; Brindisi, Margherita et al. (2018) Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand. Bioorg Med Chem Lett 28:2605-2610
Thompson, Taylor J; Han, Bumsoo (2018) Analysis of adhesion kinetics of cancer cells on inflamed endothelium using a microfluidic platform. Biomicrofluidics 12:042215
Alpsoy, Aktan; Dykhuizen, Emily C (2018) Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes. J Biol Chem 293:3892-3903
Kumari, Rashmi; Silic, Martin R; Jones-Hall, Yava L et al. (2018) Identification of RECK as an evolutionarily conserved tumor suppressor gene for zebrafish malignant peripheral nerve sheath tumors. Oncotarget 9:23494-23504
Larocque, Elizabeth A; Naganna, N; Opoku-Temeng, Clement et al. (2018) Alkynylnicotinamide-Based Compounds as ABL1 Inhibitors with Potent Activities against Drug-Resistant CML Harboring ABL1(T315I) Mutant Kinase. ChemMedChem 13:1172-1180
Poh, Scott; Chelvam, Venkatesh; Ayala-López, Wilfredo et al. (2018) Selective liposome targeting of folate receptor positive immune cells in inflammatory diseases. Nanomedicine 14:1033-1043

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