Abstract

The goal of the Biostatistics Shared Resource of the UNMC Eppley Cancer Center is to participate in the research mission of the institution by making the expertise and experience of its personnel available to Cancer Center members for planning, conducting and reporting of basic, translational, clinical, and population-based research projects. The Biostatistics Shared Resource is housed in the Biostatistics Section of the Department of Preventive and Societal Medicine. Four Ph.D. level biostatisticians and three Masters-level biostatisticians are available to Cancer Center investigators to assist in their research. Responsibilities for these collaborations have been divided amongst the biostatisticians by disease or specialty areas, so that they may develop special knowledge and expertise in these areas. Nevertheless, all members of the Biostatistical Shared Resource are available to consult with Cancer Center scientists on the design, conduct, analysis, and reporting of their research. Members of the Biostatistics Shared Resource are also members of the Statistical Department of the Children's Oncology Group, the national cooperative group conducting studies on the biology and treatment of cancer in children and adolescents. Members of the Biostatistics Shared Resource collaborate with Children's Oncology Group investigators on study design, conduct, and analysis of their research.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA036727-24
Application #
7666990
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
24
Fiscal Year
2008
Total Cost
$106,112
Indirect Cost

  Institution

Name
University of Nebraska Medical Center
Department
Type
DUNS #
168559177
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Azadmanesh, Jahaun; Borgstahl, Gloria E O (2018) A Review of the Catalytic Mechanism of Human Manganese Superoxide Dismutase. Antioxidants (Basel) 7:
Rana, Sandeep; Sonawane, Yogesh A; Taylor, Margaret A et al. (2018) Synthesis of aminopyrazole analogs and their evaluation as CDK inhibitors for cancer therapy. Bioorg Med Chem Lett 28:3736-3740
Chhonker, Yashpal S; Haney, Staci L; Matthiesen, Robert A et al. (2018) Quantitative determination of a potent geranylgeranyl diphosphate synthase inhibitor using LC-MS/MS: Derivatization and application. J Pharm Biomed Anal 153:22-28
Haney, Staci L; Chhonker, Yashpal S; Varney, Michelle L et al. (2018) Preclinical investigation of a potent geranylgeranyl diphosphate synthase inhibitor. Invest New Drugs 36:810-818
Saxena, Sugandha; Hayashi, Yuri; Wu, Lingyun et al. (2018) Pathological and functional significance of Semaphorin-5A in pancreatic cancer progression and metastasis. Oncotarget 9:5931-5943
Lockridge, Oksana; David, Emilie; Schopfer, Lawrence M et al. (2018) Purification of recombinant human butyrylcholinesterase on Hupresin®. J Chromatogr B Analyt Technol Biomed Life Sci 1102-1103:109-115
Ray, Sutapa; Coulter, Don W; Gray, Shawn D et al. (2018) Suppression of STAT3 NH2 -terminal domain chemosensitizes medulloblastoma cells by activation of protein inhibitor of activated STAT3 via de-repression by microRNA-21. Mol Carcinog 57:536-548
Souza, Nathália P; Hard, Gordon C; Arnold, Lora L et al. (2018) Epithelium Lining Rat Renal Papilla: Nomenclature and Association with Chronic Progressive Nephropathy (CPN). Toxicol Pathol 46:266-272
Payne, William M; Svechkarev, Denis; Kyrychenko, Alexander et al. (2018) The role of hydrophobic modification on hyaluronic acid dynamics and self-assembly. Carbohydr Polym 182:132-141
Kanvinde, Shrey; Chhonker, Yashpal Singh; Ahmad, Rizwan et al. (2018) Pharmacokinetics and efficacy of orally administered polymeric chloroquine as macromolecular drug in the treatment of inflammatory bowel disease. Acta Biomater 82:158-170

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