CANCER RESEARCH CAREER ENHANCEMENT AND RELATED ACTIVITIES PROJECT SUMMARY/ABSTRACT The Cancer Research Career Enhancement and Related Activities are centered in the Case Comprehensive Cancer Center (Case CCC) Office of Cancer Trainee Education and Research (OCTER), which coordinates existing research education and training activities across the consortium?s institutions, and develops new educational initiatives with emphasis on integrating cancer researchers and health care professionals. Case CCC supported programs have facilitated career enrichment activities for 1,622 cancer trainees during the last cycle, spanning career stages from high school students through junior faculty. The impact of these efforts are evidenced by: 1) the portfolio of peer-reviewed training grants in cancer research and clinical training; 2) the high-impact basic and clinical science performed by Center trainees; 3) robust trainee involvement in Center- sponsored career enrichment activities; 4) successful career advancement for all Case CCC trainees; 5) coordination of Center-wide research education and training activities by the Cancer Education and Research Committee (CERC); and 6) Center efforts to engage underrepresented minority (URM) groups at all levels, including high school and undergraduate students, to enter cancer-oriented biomedical scientific research and healthcare professions. To maintain excellence and expand Center cancer research career enrichment activities, the OCTER has developed the following three specific aims that will carry it forward in the next grant cycle:
Aim 1 : Provide cancer research career enrichment activities across the continuum of trainees.
Aim 2 : Coordinate Center-wide cancer education and training activities.
Aim 3 : Integrate cancer research mentoring and training of biomedical scientists and healthcare professionals. The Case CCC strives to provide rigorous training in cancer research as well as career enhancement activities that prepare all trainees for productive careers as biomedical cancer researchers or healthcare professionals.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA043703-28
Application #
9488757
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2018-05-10
Budget End
2019-03-31
Support Year
28
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Qiu, Zhaojun; Oleinick, Nancy L; Zhang, Junran (2018) ATR/CHK1 inhibitors and cancer therapy. Radiother Oncol 126:450-464
Elitt, Matthew S; Shick, H Elizabeth; Madhavan, Mayur et al. (2018) Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease. Stem Cell Reports 11:711-726
He, Tian; McColl, Karen; Sakre, Nneha et al. (2018) Post-transcriptional regulation of PIAS3 expression by miR-18a in malignant mesothelioma. Mol Oncol 12:2124-2135
Roche, Kathryn L; Nukui, Masatoshi; Krishna, Benjamin A et al. (2018) Selective 4-Thiouracil Labeling of RNA Transcripts within Latently Infected Cells after Infection with Human Cytomegalovirus Expressing Functional Uracil Phosphoribosyltransferase. J Virol 92:
Bedell, Hillary W; Hermann, John K; Ravikumar, Madhumitha et al. (2018) Targeting CD14 on blood derived cells improves intracortical microelectrode performance. Biomaterials 163:163-173
Nagaraj, A B; Wang, Q Q; Joseph, P et al. (2018) Using a novel computational drug-repositioning approach (DrugPredict) to rapidly identify potent drug candidates for cancer treatment. Oncogene 37:403-414
Somasegar, Sahana; Li, Li; Thompson, Cheryl L (2018) No association of reproductive risk factors with breast cancer tumor grade. Eur J Cancer Prev 27:140-143
Gu, Xiaorong; Ebrahem, Quteba; Mahfouz, Reda Z et al. (2018) Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates. J Clin Invest 128:4260-4279
Benson, Bryan L; Li, Lucy; Myers, Jay T et al. (2018) Biomimetic post-capillary venule expansions for leukocyte adhesion studies. Sci Rep 8:9328
Bosca, Federica; Bielecki, Peter A; Exner, Agata A et al. (2018) Porphyrin-Loaded Pluronic Nanobubbles: A New US-Activated Agent for Future Theranostic Applications. Bioconjug Chem 29:234-240

Showing the most recent 10 out of 1227 publications