The DNA Sequencing Shared Resource provides cost effective rapid DNA sequencing to members of the CSHL Cancer Center. Almost all members of the CSHL Cancer Center use this Shared Resource, and there has been a continuous increase in demand. By continually updating the facility we have not only been able to increase the capacity of the facility to keep up with the increased demand, but we have also been able to reduce costs. The facility began the previous grant period utilizing one capillary-based DNA sequencing instrument. With the full support of our Cancer Center Advisory Board, we are now offering Next Generation sequencing services through the Shared Resource and plan to expand this in the coming year. This will allow Cancer Center members who have smaller scale research projects to gain access to, and benefit from, this powerful technology. Throughout its evolution this Resource has provided instructions and guidance in the area of DNA sequencing and analysis to CSHL Cancer Center members.
The DNA Sequencing Shared Resource is used widely and provides basic sequencing services, as well as powerful Next Generation sequencing services, to Cancer Center members, both of which are critical for supporting the research goals of Cancer Center investigators.
|Stacchiotti, Silvia; Mir, Olivier; Le Cesne, Axel et al. (2018) Activity of Pazopanib and Trabectedin in Advanced Alveolar Soft Part Sarcoma. Oncologist 23:62-70|
|Banito, Ana; Li, Xiang; Laporte, Aimée N et al. (2018) The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma. Cancer Cell 33:527-541.e8|
|Goncalves, Marcus D; Hwang, Seo-Kyoung; Pauli, Chantal et al. (2018) Fenofibrate prevents skeletal muscle loss in mice with lung cancer. Proc Natl Acad Sci U S A 115:E743-E752|
|Hwang, Dong-Woo; Jaganathan, Anbalagan; Shrestha, Padmina et al. (2018) Chromatin-mediated translational control is essential for neural cell fate specification. Life Sci Alliance 1:e201700016|
|Knott, Simon R V; Wagenblast, Elvin; Khan, Showkhin et al. (2018) Asparagine bioavailability governs metastasis in a model of breast cancer. Nature 554:378-381|
|Biffi, Giulia; Oni, Tobiloba E; Spielman, Benjamin et al. (2018) IL-1-induced JAK/STAT signaling is antagonized by TGF-beta to shape CAF heterogeneity in pancreatic ductal adenocarcinoma. Cancer Discov :|
|Xie, Yuanyuan; Cao, Zhen; Wong, Elissa Wp et al. (2018) COP1/DET1/ETS axis regulates ERK transcriptome and sensitivity to MAPK inhibitors. J Clin Invest 128:1442-1457|
|Aznarez, Isabel; Nomakuchi, Tomoki T; Tetenbaum-Novatt, Jaclyn et al. (2018) Mechanism of Nonsense-Mediated mRNA Decay Stimulation by Splicing Factor SRSF1. Cell Rep 23:2186-2198|
|Fang, Han; Huang, Yi-Fei; Radhakrishnan, Aditya et al. (2018) Scikit-ribo Enables Accurate Estimation and Robust Modeling of Translation Dynamics at Codon Resolution. Cell Syst 6:180-191.e4|
|Lin, Kuan-Ting; Ma, Wai Kit; Scharner, Juergen et al. (2018) A human-specific switch of alternatively spliced AFMID isoforms contributes to TP53 mutations and tumor recurrence in hepatocellular carcinoma. Genome Res :|
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