The Director has the overall responsibility for the planning and operation of research at UPCI. The Associate Directors provide scientific and administrative leadership and support the Director. The Associate Directors for Basic, Clinical and Translational Research have the broad responsibilities in working with the Director of UPCI to plan the scientific directions, strengthening and expansion of existing programs, development of new programs. They also provide input in recruitment of new faculty into the programs. Through all these decisions, the focus and emphasis remain on the translational aspects of each programs and collaborative interactions between programs. Basic research occurs in all twelve CCSG programs and the Associate Directors for Basic and Translational Research are tasked with the responsibility of ensuring that the labbased research activities translate into clinical applications. The Associate Director for Clinical investigations has the critical responsibility of facilitating interdisciplinary clinical and translational research via the clinical research program. The Associate Director for Administration and Strategic Planning has the centralized role of coordinating all aspects ofthe research operations and the overall administration and management ofthe UPCI. The Associate Director for Research Services has the responsibility for oversight of all facets of the services provided by the shared facilities. Working together, the two administrative Associate Directors provide unique strength to the administrative functions ofthe cancer institute.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA047904-24
Application #
8382660
Study Section
Special Emphasis Panel (ZCA1-RTRB-L)
Project Start
Project End
Budget Start
2012-08-01
Budget End
2013-07-31
Support Year
24
Fiscal Year
2012
Total Cost
$332,382
Indirect Cost
$78,574
Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Song, Xinxin; Zhu, Shan; Chen, Pan et al. (2018) AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc- Activity. Curr Biol 28:2388-2399.e5
Leng, Shuguang; Diergaarde, Brenda; Picchi, Maria A et al. (2018) Gene Promoter Hypermethylation Detected in Sputum Predicts FEV1 Decline and All-Cause Mortality in Smokers. Am J Respir Crit Care Med 198:187-196
Zhang, Jiliang; Zhang, Shaojuan; Liu, Yang et al. (2018) Combined CB2 receptor agonist and photodynamic therapy synergistically inhibit tumor growth in triple negative breast cancer. Photodiagnosis Photodyn Ther 24:185-191
Pascal, Laura E; Wang, Yao; Zhong, Mingming et al. (2018) EAF2 and p53 Co-Regulate STAT3 Activation in Prostate Cancer. Neoplasia 20:351-363
Robinson, Andria R; Yousefzadeh, Matthew J; Rozgaja, Tania A et al. (2018) Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging. Redox Biol 17:259-273
Overacre-Delgoffe, Abigail E; Vignali, Dario A A (2018) Treg Fragility: A Prerequisite for Effective Antitumor Immunity? Cancer Immunol Res 6:882-887
Nelson, Ashley M; Carew, Nolan T; Smith, Sage M et al. (2018) RNA Splicing in the Transition from B Cells to Antibody-Secreting Cells: The Influences of ELL2, Small Nuclear RNA, and Endoplasmic Reticulum Stress. J Immunol 201:3073-3083
Pore, Subrata K; Hahm, Eun-Ryeong; Latoche, Joseph D et al. (2018) Prevention of breast cancer-induced osteolytic bone resorption by benzyl isothiocyanate. Carcinogenesis 39:134-145
Kumar, Dhruv; New, Jacob; Vishwakarma, Vikalp et al. (2018) Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression. Cancer Res 78:3769-3782
Weir, Mark C; Shu, Sherry T; Patel, Ravi K et al. (2018) Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo. ACS Chem Biol 13:1551-1559

Showing the most recent 10 out of 1187 publications