?Mass Spectrometry Shared Resource The purpose of the Mass Spectrometry Shared Resource (MSSR) is to provide the Mays Cancer Center (MCC) members and University of Texas Health San Antonio (UT Health SA) investigators with comprehensive, state- of-the-art support for characterization and quantification of proteins, metabolites and other biomedically important molecules using mass spectrometry. The MSSR has been a Cancer Center Shared Resource since 1998 and is housed in 1,034 sq. ft. of space in two laboratories on the Long (main) campus of the UT Health SA. The MSSR is jointly managed by the UT Health SA and the MCC. Proteomics is the main focus of the MSSR, providing a wide range of services that include molecular mass determination, protein identification and relative quantification, and identification/localization of sites of protein modification. The scope of its service has expanded significantly over the years with the acquisition of new equipment supported by numerous NIH Instrumentation grants and by funds from the UT System. The Shared Resource also offers consultation at all stages of an investigation as well as training to MCC investigators. The MSSR has been directed by Susan T. Weintraub, Ph.D., since 1998. Dr. Weintraub has extensive experience in utilizing mass spectrometry for innovative research and served in several national leadership roles including President of the American Society for Mass Spectrometry. The MSSR team has exceptional expertise in the use of mass spectrometry to solve important cancer-related questions. During the last funding period, the MSSR serviced 31 peer-review funded MCC members. Its annual usage by peer-review funded MCC members averaged 27%.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA054174-25
Application #
10025089
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
1997-08-01
Project End
2025-07-31
Budget Start
2020-08-01
Budget End
2021-07-31
Support Year
25
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Texas Health Science Center
Department
Type
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Yu, Xiaojie; Zhang, Yiqiang; Ma, Xiuye et al. (2018) miR-195 potentiates the efficacy of microtubule-targeting agents in non-small cell lung cancer. Cancer Lett 427:85-93
Ankerst, Donna P; Goros, Martin; Tomlins, Scott A et al. (2018) Incorporation of Urinary Prostate Cancer Antigen 3 and TMPRSS2:ERG into Prostate Cancer Prevention Trial Risk Calculator. Eur Urol Focus :
Arora, Sukeshi Patel; Mahalingam, Devalingam (2018) Immunotherapy in colorectal cancer: for the select few or all? J Gastrointest Oncol 9:170-179
Arellano, Luisa M; Arora, Sukeshi Patel (2018) Systemic Treatment of Advanced Hepatocellular Carcinoma in Older Adults. J Nat Sci 4:
Du, Liqin; Zhao, Zhenze; Suraokar, Milind et al. (2018) LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer. Oncotarget 9:29601-29618
Ankerst, Donna P; Straubinger, Johanna; Selig, Katharina et al. (2018) A Contemporary Prostate Biopsy Risk Calculator Based on Multiple Heterogeneous Cohorts. Eur Urol 74:197-203
Sun, Xiujie; Gupta, Kshama; Wu, Bogang et al. (2018) Tumor-extrinsic discoidin domain receptor 1 promotes mammary tumor growth by regulating adipose stromal interleukin 6 production in mice. J Biol Chem 293:2841-2849
Horning, Aaron M; Wang, Yao; Lin, Che-Kuang et al. (2018) Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle-Related Transcription and Attenuated Androgen Response. Cancer Res 78:853-864
Gong, Siqi; Tomusange, Khamis; Kulkarni, Viraj et al. (2018) Anti-HIV IgM protects against mucosal SHIV transmission. AIDS 32:F5-F13
Gelfond, Jonathan; Goros, Martin; Hernandez, Brian et al. (2018) A System for an Accountable Data Analysis Process in R. R J 10:6-21

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