QUANTITATIVE SCIENCES AND POPULATION RESEARCH GROUP CORE 013 ? RESEARCH INFORMATICS SHARED RESOURCE PROJECT SUMMARY / ABSTRACT The mission of the Vanderbilt-Ingram Cancer Center (VICC) Research Informatics Shared Resource (RISR) is to catalyze the research productivity of VICC investigators by providing common informatics services in a standardized fashion. These services include software development, shared research applications and shared data storage. The services currently provided by the RISR include technology support, application support, FISMA hosting, database support and clinical informatics support to enable clinical decision-making using genetic information (e.g., mycancergenome.org and other VICC applications). Additionally, the RISR supports clinical trials management via services for protocol, calendar and eCRF setup. Finally, custom development, data management and reporting services are available and managed through a project management lifecycle. A major focus of the RISR is secondary use of data sources such as NCI PDQ, tumor registry and industry- specific repositories, leveraging institutional resources and selection of tools based on vendor capabilities and reuse of technology solutions. Several of the significant activities within the RISR support the clinical trials management system along with data integration for use within reporting tools and dashboards. Additionally, the custom developed My Cancer Genome and VICC.org systems have been designed by the RISR to complement and integrate with CTSA and enterprise tools such as REDCap and Microsoft SharePoint.
The specific aims for the upcoming project period include:
Aim 1) Enhance RISR?s cancer-centric research data mart;
Aim 2) Improve investigator outreach;
Aim 3) Standardize a portfolio of tools to enhance clinical trials and cancer discovery.

Public Health Relevance

QUANTITATIVE SCIENCES AND POPULATION RESEARCH GROUP CORE 013 ? RESEARCH INFORMATICS SHARED RESOURCE PROJECT NARRATIVE Per the PAR-13-386 FOA, the project narrative is not applicable for the Research Informatics Shared Resource.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA068485-19
Application #
8934386
Study Section
Subcommittee G - Education (NCI)
Project Start
1997-09-17
Project End
2020-08-31
Budget Start
2015-09-07
Budget End
2016-08-31
Support Year
19
Fiscal Year
2015
Total Cost
$123,653
Indirect Cost
$44,893
Name
Vanderbilt University Medical Center
Department
Type
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Takata, Yumie; Xiang, Yong-Bing; Burk, Raymond F et al. (2018) Plasma selenoprotein P concentration and lung cancer risk: results from a case-control study nested within the Shanghai Men's Health Study. Carcinogenesis 39:1352-1358
Feng, Yinnian; Reinherz, Ellis L; Lang, Matthew J (2018) ?? T Cell Receptor Mechanosensing Forces out Serial Engagement. Trends Immunol 39:596-609
Sucre, Jennifer M S; Deutsch, Gail H; Jetter, Christopher S et al. (2018) A Shared Pattern of ?-Catenin Activation in Bronchopulmonary Dysplasia and Idiopathic Pulmonary Fibrosis. Am J Pathol 188:853-862
Rogers, Meredith C; Lamens, Kristina D; Shafagati, Nazly et al. (2018) CD4+ Regulatory T Cells Exert Differential Functions during Early and Late Stages of the Immune Response to Respiratory Viruses. J Immunol 201:1253-1266
Rosenberg, Adam J; Nickels, Michael L; Schulte, Michael L et al. (2018) Automated radiosynthesis of 5-[11C]l-glutamine, an important tracer for glutamine utilization. Nucl Med Biol 67:10-14
Dean, Donnatesa A L; Griffith, Derek M; McKissic, Sydika A et al. (2018) Men on the Move-Nashville: Feasibility and Acceptability of a Technology-Enhanced Physical Activity Pilot Intervention for Overweight and Obese Middle and Older Age African American Men. Am J Mens Health 12:798-811
Choi, Eunyoung; Lantz, Tyler L; Vlacich, Gregory et al. (2018) Lrig1+ gastric isthmal progenitor cells restore normal gastric lineage cells during damage recovery in adult mouse stomach. Gut 67:1595-1605
Parl, Fritz F; Crooke, Philip S; Plummer Jr, W Dale et al. (2018) Genomic-Epidemiologic Evidence That Estrogens Promote Breast Cancer Development. Cancer Epidemiol Biomarkers Prev 27:899-907
Marks, Christian R; Shonesy, Brian C; Wang, Xiaohan et al. (2018) Activated CaMKII? Binds to the mGlu5 Metabotropic Glutamate Receptor and Modulates Calcium Mobilization. Mol Pharmacol 94:1352-1362
Singh, Kshipra; Coburn, Lori A; Asim, Mohammad et al. (2018) Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses. Cancer Res 78:4303-4315

Showing the most recent 10 out of 2462 publications