The Bioanalytical/Pharmacokinetics Shared Resource (BPSR) is a shared resource that provides Knight members with access to state-of-the art liquid chromatography tandem mass spectrometry (LC-MS/MS) and gas chromatography mass spectrometry (GC-MS). The BPSR provides expert consultation on the design of analytical methods and pharmacokinetic studies and assistance with the analysis of PK data.
The Specific Aims of the facility are: 1) to provide Knight members access to instrumentation that is maintained for small molecule analysis and includes LC-MS/MS and GC-MS instruments;2) to provide Knight members with a full service laboratory to develop analytical methods, prepare samples and provide data analysis for both clinical and basic science investigations;3) to provide Knight members with assistance in the design and interpretation of pharmacokinetic studies for both animal models and Phase 1 investigations.

Public Health Relevance

The study of the absorption, distribution, metabolism and elimination of established and experimental drugs is essential to the Knight Cancer Institute's program of personalized medicine. The BPSR enables investigators to ask quantitative questions about small molecules in all phases of translational research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA069533-14
Application #
8340106
Study Section
Subcommittee G - Education (NCI)
Project Start
2011-07-20
Project End
2016-06-30
Budget Start
2011-07-20
Budget End
2012-06-30
Support Year
14
Fiscal Year
2011
Total Cost
$61,257
Indirect Cost
Name
Oregon Health and Science University
Department
Type
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
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