Cancer Epidemiology Research in the Cancer Epidemiology Program focuses on the population-based study of cancer etiology, health services and outcomes, and cancer prevention and control. The overall goal of program members is to save lives by increasing our understanding of what causes cancer, promoting cancer prevention behaviors and early detection and treatment, and developing improved diagnostic tests and treatments. When cancer cannot be prevented, we are also interested in research that will extend the quantity and quality of life for the cancer survivor. There are three major overlapping themes the Program's research. The first theme involves cancer etiology. Research areas within this theme include the study of environmental exposures and cancer, other biologic causes of cancer, and evaluation of the burden of cancer. The second theme involves cancer health services &outcomes. Research areas within this theme include evaluation of the delivery of cancer services, and assessment of how biobehavior and neuropsychiatric factors impact on the burden of cancer. The third theme involves cancer prevention and control. Research areas within this theme focus on studies exploring risk reduction and cancer screening. In population science, scientific achievements can be measured by their translation into activities that improve the health of the public. In this regard, after 20 years of residential radon and lung cancer epidemiologic research here and elsewhere, the World Health Organization has been convinced and is implementing an international initiative to reduce indoor radon risks. Also the strengths of the study design and findings relating to pesticides and cancer in the Agricultural Health Study, where two-thirds of participants are lowans, has led the US EPA to announce that epidemiologic data will be used in its risk assessment of pesticides, marking a significant departure from traditional EPA practice, which has focused on short-term bioassays and animal testing in risk assessment. This highly interactive program consists of 33 members from 8 basic science and 9 clinical departments in 5 Colleges. Peer reviewed, research funding forthis program totals $6,841,168 with $2,339,558 coming from the NCI. Program members published 443 cancer-related papers over the prior funding period. Of these publications, 15% were intraprogrammatic, 18% were interprogrammatic and 7% were both intra and interprogrammatic, for a total of 39% collaborative publications.

Public Health Relevance

Epidemiology provides research approaches for evaluating cancer in human populations. We utilize this to better understand what causes cancer to develop, to evaluate and compare the health services people with cancer receive and the outcomes resulting from these services in terms of quality and quantity of life, and ultimately how to take this knowledge and provide for improved approaches to controlling and preventing this disease, particularly in rural, agricultural populations as seen in lowa.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA086862-12S1
Application #
8533958
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
2016-03-31
Budget Start
2012-05-03
Budget End
2013-03-31
Support Year
12
Fiscal Year
2012
Total Cost
$3,000
Indirect Cost
$1,013
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Lee, Jennifer E; Anderson, Carryn M; Perkhounkova, Yelena et al. (2018) Transcutaneous Electrical Nerve Stimulation Reduces Resting Pain in Head and Neck Cancer Patients: A Randomized and Placebo-Controlled Double-Blind Pilot Study. Cancer Nurs :
McAtee, Caitlin O; Booth, Christine; Elowsky, Christian et al. (2018) Prostate tumor cell exosomes containing hyaluronidase Hyal1 stimulate prostate stromal cell motility by engagement of FAK-mediated integrin signaling. Matrix Biol :
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Brogden, Kim A; Parashar, Deepak; Hallier, Andrea R et al. (2018) Genomics of NSCLC patients both affirm PD-L1 expression and predict their clinical responses to anti-PD-1 immunotherapy. BMC Cancer 18:225
Do, Anh-Vu; Worthington, Kristan S; Tucker, Budd A et al. (2018) Controlled drug delivery from 3D printed two-photon polymerized poly(ethylene glycol) dimethacrylate devices. Int J Pharm 552:217-224
Adams, Swann Arp; Rohweder, Catherine L; Leeman, Jennifer et al. (2018) Use of Evidence-Based Interventions and Implementation Strategies to Increase Colorectal Cancer Screening in Federally Qualified Health Centers. J Community Health :

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