Central Microscopy Microscopy remains central to both laboratory and clinical cancer research. The principal goal of the Central Microscopy Research Facility (CMRF) is to provide services and instruction to HCCC investigators interested in using microscopy technology for cancer research. The CMRF provides technical assistance for labor intensive techniques and ready access to highly specialized and expensive equipment. It supports cancer research being done by members of all 6 research programs. Specific services available to HCCC investigators include expertise related to tissue preparation, fixation and staining for: 1) Light microscopy 2) Histochemical and fluorescence microscopy 3) Confocal, multiphoton and electron microscopy 4) In situ hybridization 5) Elemental and chemical characterization 5) In vivo small animal imaging using the IVIS imaging system The CMRF provides consultation and assistance to HCCC investigators in the development and application of new and specialized morphological methods relevant to cancer research. In 2009, 80 HCCC members with peer reviewed funding utilized the CMRF.

Public Health Relevance

Light, fluorescence, confocal, and electron microscopy are central tools for many aspects of laboratory and clinical cancer research. The CMRF provides a comprehensive, state-of-the-art array of microscopy instrumentation and techniques to HCCC members conducting cancer research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA086862-14
Application #
8640100
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
14
Fiscal Year
2014
Total Cost
$74,843
Indirect Cost
$28,740
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Vijapura, Charmi; Yang, Limin; Xiong, Jinhu et al. (2018) Imaging Features of Nonmalignant and Malignant Architectural Distortion Detected by Tomosynthesis. AJR Am J Roentgenol 211:1397-1404
Brooks, Nathan A; Boland, Riley S; Strigenz, Michael E et al. (2018) Nongenitourinary complications associated with robot-assisted laparoscopic and radical retropubic prostatectomy: A single institution assessment of 1,100 patients over 11 years. Urol Oncol 36:501.e9-501.e13
Sandgren, Jeremy A; Deng, Guorui; Linggonegoro, Danny W et al. (2018) Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice. JCI Insight 3:
Jiang, Cheng-Fei; Shi, Zhu-Mei; Li, Dong-Mei et al. (2018) Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer. Mol Cancer 17:83
Moss, Jennifer L; Xiao, Qian; Matthews, Charles E (2018) Patterns of cancer-related health behaviors among middle-aged and older adults: Individual- and area-level socioeconomic disparities. Prev Med 115:31-38
Monga, Varun; Maliske, Seth M; Kaleem, Hassan et al. (2018) Discrepancy between treatment goals documentation by oncologists and their understanding among cancer patients under active treatment with chemotherapy. Eur J Cancer Care (Engl) :e12973
Swami, Umang; Lenert, Petar; Furqan, Muhammad et al. (2018) Atezolizumab after Nivolumab-Induced Inflammatory Polyarthritis: Can Anti-PD-L1 Immunotherapy Be Administered after Anti-PD-1-Related Immune Toxicities? J Thorac Oncol 13:e102-e103
Seaman, Aaron T; Dukes, Kimberly; Hoffman, Richard M et al. (2018) The complicated 'Yes': Decision-making processes and receptivity to lung cancer screening among head and neck cancer survivors. Patient Educ Couns 101:1741-1747
Shields, Anthony F; Jacobs, Paula M; Sznol, Mario et al. (2018) Immune Modulation Therapy and Imaging: Workshop Report. J Nucl Med 59:410-417
Alexander, Matthew S; Wilkes, Justin G; Schroeder, Samuel R et al. (2018) Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer. Cancer Res 78:6838-6851

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