Clinical Trials Support Core The Clinical Trials Support Core (CTSC) is a shared resource available to all members of the HCCC. It is designed to facilitate execution of high quality clinical cancer investigation including both interventional and correlative science studies. The CTSC enhances interaction among HCCC members and provides for easy assembly of multi-departmental teams needed for collaboration on innovative protocols. The CTSC is composed of dedicated staff with expertise in protocol management and study coordination. Administratively, the Director of the CTSC works closely with the Assistant Director for Clinical Services, and reports to the Associate Director for Clinical and Translational Research. The CTSC provides investigators with appropriate routing of protocols through the various internal regulatory committees including the HCCC Protocol Review and Monitoring Committee, assists the investigator in protocol modifications and reporting of adverse events for ongoing clinical studies, and supplies staff with expertise in data management. The CTSC also provides support for translational research by assisting in the procurement of blood and other not surgical tissues for investigators. It participates in posting protocol lists and supporting internal communication regarding ongoing studies, as well as statistical reporting on accrual. A chargeback system is used to compensate the CTSC for support of most clinical trials run through the CTSC. The core also supports innovative, early phase clinical trials for which there is no other source of support.

Public Health Relevance

The Clinical Trials Support Core provides a centralized resource for investigators interested in clinical and translational cancer research. It is a vital shared resource if we are to translate basic science advances in cancer to the clinic.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA086862-14
Application #
8640106
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
14
Fiscal Year
2014
Total Cost
$132,029
Indirect Cost
$28,740
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Davis, Lauren Z; Cuneo, Michaela; Thaker, Premal H et al. (2018) Changes in spiritual well-being and psychological outcomes in ovarian cancer survivors. Psychooncology 27:477-483
Pearson, Jennifer L; Amato, Michael S; Papandonatos, George D et al. (2018) Exposure to positive peer sentiment about nicotine replacement therapy in an online smoking cessation community is associated with NRT use. Addict Behav 87:39-45
Mobley, Erin M; Foster, Kristin J; Terry, William W (2018) Identifying and Understanding the Gaps in Care Experienced by Adolescent and Young Adult Cancer Patients at the University of Iowa Hospitals and Clinics. J Adolesc Young Adult Oncol 7:592-603
Holahan, Heather M; Farah, Ronda S; Fitz, Sara et al. (2018) Health-related quality of life in patients with cutaneous T-cell lymphoma? Int J Dermatol 57:1314-1319
Kurth, Ann E; Krist, Alex H; Borsky, Amanda E et al. (2018) U.S. Preventive Services Task Force Methods to Communicate and Disseminate Clinical Preventive Services Recommendations. Am J Prev Med 54:S81-S87
Gadupudi, Gopi S; Elser, Benjamin A; Sandgruber, Fabian A et al. (2018) PCB126 Inhibits the Activation of AMPK-CREB Signal Transduction Required for Energy Sensing in Liver. Toxicol Sci 163:440-453
Strouse, Christopher; Mangalam, Ashutosh; Zhang, Jun (2018) Bugs in the system: bringing the human microbiome to bear in cancer immunotherapy. Gut Microbes :1-4
White, Katherine A; Swier, Vicki J; Cain, Jacob T et al. (2018) A porcine model of neurofibromatosis type 1 that mimics the human disease. JCI Insight 3:
Tota, Joseph E; Engels, Eric A; Madeleine, Margaret M et al. (2018) Risk of oral tongue cancer among immunocompromised transplant recipients and human immunodeficiency virus-infected individuals in the United States. Cancer 124:2515-2522
Klaren, William D; Vine, David; Vogt, Stefan et al. (2018) Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25:16427-16433

Showing the most recent 10 out of 1080 publications