The goals of the Administrative Core are clearly distinct from those of the scientific cores. Its major tasks are to organize, support, and manage the UIUC Neuroproteomics Center on Cell-Cell Signaling. Primary activities include resource management, education and outreach, and datasharing oversight. The Administrative Core brings together the individual core Pis and the biological users with the Center's internal advisory committee and external advisory board. The first area described is the Center's organization and operational plans, with an emphasis on facilitating communication between Center personnel and the users. After all, the goal is to establish a logically interconnected neuroproteomics center and not simply to manage separate projects undertaken by individual investigators. Successful and continuing efforts to acquire and upgrade our measurement infrastructure are described. In addition, efforts in outreach and training, both for users of the Center and for the entire neuroscience and drug abuse research communities are highlighted. We also present an overview of the UIUC Center and the relationship between the cores. Several neuroproteomics centers were initiated four years ago by NIDA with the stated goals to provide neurobiologists with the ability to (1) benefit from proteomics experiments, (2) build a cadre of proteomics experts who will develop expertise in analyzing neural samples, and (3) develop and improve existing technologies as they relate to neurobiology. The Administrative Core is the cohesive force that binds all three of these efforts in the UIUC Neuroproteomics Center on Cell-Cell Signaling.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Center Core Grants (P30)
Project #
5P30DA018310-07
Application #
8080945
Study Section
Special Emphasis Panel (ZDA1)
Project Start
Project End
Budget Start
2010-06-01
Budget End
2011-05-31
Support Year
7
Fiscal Year
2010
Total Cost
$104,730
Indirect Cost
Name
University of Illinois Urbana-Champaign
Department
Type
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820
Neumann, Elizabeth K; Comi, Troy J; Spegazzini, Nicolas et al. (2018) Multimodal Chemical Analysis of the Brain by High Mass Resolution Mass Spectrometry and Infrared Spectroscopic Imaging. Anal Chem 90:11572-11580
Yang, Ning; Anapindi, Krishna D B; Rubakhin, Stanislav S et al. (2018) Neuropeptidomics of the Rat Habenular Nuclei. J Proteome Res 17:1463-1473
Tillmaand, Emily G; Sweedler, Jonathan V (2018) Integrating Mass Spectrometry with Microphysiological Systems for Improved Neurochemical Studies. Microphysiol Syst 2:
Greenwood, Michael P; Greenwood, Mingkwan; Romanova, Elena V et al. (2018) The effects of aging on biosynthetic processes in the rat hypothalamic osmoregulatory neuroendocrine system. Neurobiol Aging 65:178-191
Shen, Mei; Qu, Zizheng; DesLaurier, Justin et al. (2018) Single Synaptic Observation of Cholinergic Neurotransmission on Living Neurons: Concentration and Dynamics. J Am Chem Soc 140:7764-7768
Sorokina, Anastasia M; Saul, Michael; Goncalves, Tassia M et al. (2018) Striatal transcriptome of a mouse model of ADHD reveals a pattern of synaptic remodeling. PLoS One 13:e0201553
Anapindi, Krishna D B; Romanova, Elena V; Southey, Bruce R et al. (2018) Peptide identifications and false discovery rates using different mass spectrometry platforms. Talanta 182:456-463
Southey, Bruce R; Romanova, Elena V; Rodriguez-Zas, Sandra L et al. (2018) Bioinformatics for Prohormone and Neuropeptide Discovery. Methods Mol Biol 1719:71-96
Neumann, Elizabeth K; Do, Thanh D; Comi, Troy J et al. (2018) Exploring the Fundamental Structures of Life: Non-targeted, Chemical Analysis of Single Cells and Subcellular Structures. Angew Chem Int Ed Engl :
Welle, Theresa M; Alanis, Kristen; Colombo, Michelle L et al. (2018) A high spatiotemporal study of somatic exocytosis with scanning electrochemical microscopy and nanoITIES electrodes. Chem Sci 9:4937-4941

Showing the most recent 10 out of 227 publications