The Administrative Component supports the overall mission of the Penn DRC to prevent, treat, and cure diabetes mellitus. Its goal is to ensure that the DRC operates smoothly, effectively, and ethically while creating and nurturing the best possible environment for interdisciplinary basic and clinical diabetes research among its participating investigators. To achieve this goal, the DRC Administrative Component has the following Speciifc Aims: 1) Provide vision and leadership for the Penn DRC;2) Provide scientific direction for Penn DRC cores and activities;3) Foster interactions among DRC investigators;4) Represent the Penn DRC and its mission within and outside the University of Pennsylvania;5) Oversee the finances of the Penn DRC;and 6) Foster the next generation of diabetes researchers. The Administrative Component governs the DRC via a defined organizational structure that includes the Director and Associate Director, an Executive Committee, a Committee of Core Directors, and external as well as internal advisory boards. It coordinates and publicizes the Scientific Cores, Pilot and Feasibility Grant Program, and Enrichment Program that advance diabetes research by providing unique resources and facilitating communication and collaboration among the diverse group of diabetes-oriented basic and translational researchers that comprise the Penn DRC Research Base. The strong and responsive Administrative Component is critical to maintain the diabetes research program at the Penn DRC at the forefront of biomedical science.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK019525-38
Application #
8638927
Study Section
Special Emphasis Panel (ZDK1-GRB-S)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
38
Fiscal Year
2014
Total Cost
$528,937
Indirect Cost
$96,661
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Correnti, Jason M; Gottshall, Lauren; Lin, Annie et al. (2018) Ethanol and C2 ceramide activate fatty acid oxidation in human hepatoma cells. Sci Rep 8:12923
Williams, Bianca; Correnti, Jason; Oranu, Amanke et al. (2018) A novel role for ceramide synthase 6 in mouse and human alcoholic steatosis. FASEB J 32:130-142
Qiu, Chengxiang; Huang, Shizheng; Park, Jihwan et al. (2018) Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease. Nat Med 24:1721-1731
Cohen, Daniel M; Lim, Hee-Woong; Won, Kyoung-Jae et al. (2018) Shared nucleotide flanks confer transcriptional competency to bZip core motifs. Nucleic Acids Res 46:8371-8384
Davila, Antonio; Liu, Ling; Chellappa, Karthikeyani et al. (2018) Nicotinamide adenine dinucleotide is transported into mammalian mitochondria. Elife 7:
Abu-Gazala, Samir; Horwitz, Elad; Ben-Haroush Schyr, Rachel et al. (2018) Sleeve Gastrectomy Improves Glycemia Independent of Weight Loss by Restoring Hepatic Insulin Sensitivity. Diabetes 67:1079-1085
Zhao, Juanjuan; Lupino, Katherine; Wilkins, Benjamin J et al. (2018) Genomic integration of ERR?-HNF1? regulates renal bioenergetics and prevents chronic kidney disease. Proc Natl Acad Sci U S A 115:E4910-E4919
Pickett-Blakely, Octavia; Young, Kimberly; Carr, Rotonya M (2018) Micronutrients in Nonalcoholic Fatty Liver Disease Pathogenesis. Cell Mol Gastroenterol Hepatol 6:451-462
Kameswaran, Vasumathi; Golson, Maria L; Ramos-Rodríguez, Mireia et al. (2018) The Dysregulation of the DLK1-MEG3 Locus in Islets From Patients With Type 2 Diabetes Is Mimicked by Targeted Epimutation of Its Promoter With TALE-DNMT Constructs. Diabetes 67:1807-1815
Huang, Chen; Walker, Emily M; Dadi, Prasanna K et al. (2018) Synaptotagmin 4 Regulates Pancreatic ? Cell Maturation by Modulating the Ca2+ Sensitivity of Insulin Secretion Vesicles. Dev Cell 45:347-361.e5

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