The mission of the Washington University School of Medicine (WUMS) Diabetes Research Center (DRC) is to support and enhance research in diabetes and related metabolic diseases through Biomedical Research Core services reflecting the evolving needs of diabetes investigators, a vibrant Pilot &Feasibility Program and a dynamic Enrichment Program. Now in Its 35th year of continuous NIDDK funding, this DRC is located at an outstanding research institution with a longstanding tradition of excellence in diabetes investigation. The WUMS DRC Research Base is organized in three Focus Groups: Metabolic Regulation, Complications, and Islet Biology &Immunology. Investigators from each of these groups participate in DRC programs that address two central, interacting scientific themes-a) Approaches Across the Translational Spectrum, and b) Prevention of Diabetes Complications. Evidence that the WUMS DRC continues to successfully pursue the mission outlined in this renewal application Includes a record of outstanding productivity reflected by publications and peer-reviewed funding in diabetes and related research. Our research strategy will build on these accomplishments by: 1. Creating an environment that supports important as well as innovative research In diabetes and related metabolic disorders; 2. Supporting cutting edge basic and clinical research related to etiology, pathogenesis, prevention and cure of diabetes; 3. Raising awareness and interest in fundamental and clinical diabetes research in addition to enhancing multldisciplinary approaches to diabetes and its complications;and 4. Translating new knowledge in diabetes to improved treatment of patients with diabetes.

Public Health Relevance

Diabetes and related metabolic disorders of obesity, insulin resistance, and metabolic syndrome are complex, systemic diseases involving environmental arid genetic Influences. The infrastructure and support of the DRC, as well as the collaborative nature of the DRC, are designed to foster multldisciplinary approaches across the translational spectrum to achieve progress in understanding the pathophysiology of these disorders and to develop of new treatments, cures and preventive strategies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK020579-36
Application #
8435821
Study Section
Special Emphasis Panel (ZDK1-GRB-S (O2))
Program Officer
Hyde, James F
Project Start
1996-12-01
Project End
2017-11-30
Budget Start
2012-12-01
Budget End
2013-11-30
Support Year
36
Fiscal Year
2013
Total Cost
$1,697,636
Indirect Cost
$516,391
Name
Washington University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
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