Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK063609-05
Application #
7509439
Study Section
Special Emphasis Panel (ZDK1-GRB-7 (O1))
Project Start
2007-02-01
Project End
2008-01-31
Budget Start
2007-02-01
Budget End
2009-01-31
Support Year
5
Fiscal Year
2007
Total Cost
$112,971
Indirect Cost
Name
University of Virginia
Department
Type
DUNS #
065391526
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Galkina, Elena V; Butcher, Matthew; Keller, Susanna R et al. (2012) Accelerated atherosclerosis in Apoe-/- mice heterozygous for the insulin receptor and the insulin receptor substrate-1. Arterioscler Thromb Vasc Biol 32:247-56
Cutchins, Alexis; Harmon, Daniel B; Kirby, Jennifer L et al. (2012) Inhibitor of differentiation-3 mediates high fat diet-induced visceral fat expansion. Arterioscler Thromb Vasc Biol 32:317-24
Corbin, Kathryn L; Hall, Thomas E; Haile, Ruth et al. (2011) A novel fluorescence imaging approach for comparative measurements of pancreatic islet function in vitro. Islets 3:14-20
Roland, Alison V; Nunemaker, Craig S; Keller, Susanna R et al. (2010) Prenatal androgen exposure programs metabolic dysfunction in female mice. J Endocrinol 207:213-23
Johnson, Michael L; Veldhuis, Paula P; Grimmichova, Tereza et al. (2010) Validation of a deconvolution procedure (AutoDecon) for identification and characterization of fasting insulin secretory bursts. J Diabetes Sci Technol 4:1205-13
Crim, William S; Wu, Runpei; Carter, Jeffrey D et al. (2010) AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets. Mol Cell Endocrinol 323:246-55
Dula, Stacey B; Jecmenica, Mladen; Wu, Runpei et al. (2010) Evidence that low-grade systemic inflammation can induce islet dysfunction as measured by impaired calcium handling. Cell Calcium 48:133-42
Cole, Banumathi K; Keller, Susanna R; Wu, Runpei et al. (2010) Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice. Hypertension 55:715-21
Kim, Hyun Bae; Kumar, Anil; Wang, Lifu et al. (2010) Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors. Mol Cell Biol 30:3126-39
Guimont-Desrochers, Fanny; Cappello, Zachary John; Chagnon, Miguel et al. (2009) Cutting edge: genetic characterization of IFN-producing killer dendritic cells. J Immunol 182:5193-7

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