Abstract

The Animal Exposure Facility Core provides Center investigators with numerous inhalation exposure technologies, instrumentation, and consultation services to enhance their environmental air pollution research. Established over 50 years ago, NYU's inhalation chamber facility is one of largest and oldest inhalation exposure systems in academia. With NIEHS Center, NIH, and institutional support, this Facility Core has been continually updated to serve the evolving needs of researchers studying all aspects of air pollution research. The goal of this Core is to provide support for specialized inhalation exposures of rodent models of human disease. This support includes the generation and monitoring of routine and unique pollutant gases and particles, safe handling of treated animals, and development of novel exposure technologies.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES000260-56
Application #
9902434
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
56
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016

  Publications

Chen, Danqi; Fang, Lei; Li, Hongjie et al. (2018) The effects of acetaldehyde exposure on histone modifications and chromatin structure in human lung bronchial epithelial cells. Environ Mol Mutagen 59:375-385
Hua, Xiaohui; Xu, Jiheng; Deng, Xu et al. (2018) New compound ChlA-F induces autophagy-dependent anti-cancer effect via upregulating Sestrin-2 in human bladder cancer. Cancer Lett 436:38-51
Choi, Byeong Hyeok; Philips, Mark R; Chen, Yuan et al. (2018) K-Ras Lys-42 is crucial for its signaling, cell migration, and invasion. J Biol Chem 293:17574-17581
Peng, Minggang; Wang, Jingjing; Zhang, Dongyun et al. (2018) PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein. Oncogene :
Jose, Cynthia C; Jagannathan, Lakshmanan; Tanwar, Vinay S et al. (2018) Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1. Mol Carcinog 57:794-806
Choi, Byeong Hyeok; Chen, Changyan; Philips, Mark et al. (2018) RAS GTPases are modified by SUMOylation. Oncotarget 9:4440-4450
Li, Xin; Tian, Zhongxian; Jin, Honglei et al. (2018) Decreased c-Myc mRNA Stability via the MicroRNA 141-3p/AUF1 Axis Is Crucial for p63? Inhibition of Cyclin D1 Gene Transcription and Bladder Cancer Cell Tumorigenicity. Mol Cell Biol 38:
Jung, Seungyoun; Allen, Naomi; Arslan, Alan A et al. (2018) Anti-Müllerian hormone and risk of ovarian cancer in nine cohorts. Int J Cancer 142:262-270
Guo, Xirui; Huang, Haishan; Jin, Honglei et al. (2018) ISO, via Upregulating MiR-137 Transcription, Inhibits GSK3?-HSP70-MMP-2 Axis, Resulting in Attenuating Urothelial Cancer Invasion. Mol Ther Nucleic Acids 12:337-349
Weng, Mao-Wen; Lee, Hyun-Wook; Park, Sung-Hyun et al. (2018) Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis. Proc Natl Acad Sci U S A 115:E6152-E6161

Showing the most recent 10 out of 407 publications