Abstract

The objective of the Core is to provide EHSC investigators who complement the University of Rochester with a transgenic mouse facility core. Services include the following: 1) consultation to assist with the design, the establishment and the perpetuation of genetically modified mouse lines, 2) technical assistance with identification and maintenance of mouse lines, and 3) assistance with behavioral testing. The facility appears to be a """"""""full-service"""""""" transgenic mouse core offering a variety of services including generation of transgenic mice by pronuclear DNA microinjection or by gene targeting in ES cells. The facility maintains pedigrees of mouse colonies, offers embryo cryopreservation and rederivation of mouse lines. The Core is staffed by two technical assistants at 90% FTE and 35% FTE and they are supervised by Dr. Stripp (10%).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES001247-28
Application #
6576568
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
2002-04-01
Project End
2003-03-31
Budget Start
Budget End
Support Year
28
Fiscal Year
2002
Total Cost
$228,547
Indirect Cost

  Institution

Name
University of Rochester
Department
Type
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

Begolly, Sage; Olschowka, John A; Love, Tanzy et al. (2018) Fractionation enhances acute oligodendrocyte progenitor cell radiation sensitivity and leads to long term depletion. Glia 66:846-861
Korfmacher, Katrina Smith; Holt, Kathleen D (2018) The Potential for Proactive Housing Inspections to Inform Public Health Interventions. J Public Health Manag Pract 24:444-447
Wong, Elissa L; Lutz, Nina M; Hogan, Victoria A et al. (2018) Developmental alcohol exposure impairs synaptic plasticity without overtly altering microglial function in mouse visual cortex. Brain Behav Immun 67:257-278
Barrett, Emily S; Vitek, Wendy; Mbowe, Omar et al. (2018) Allostatic load, a measure of chronic physiological stress, is associated with pregnancy outcomes, but not fertility, among women with unexplained infertility. Hum Reprod 33:1757-1766
Franchini, Anthony M; Lawrence, B Paige (2018) Environmental exposures are hidden modifiers of anti-viral immunity. Curr Opin Toxicol 10:54-59
van den Dries, Michiel A; Pronk, Anjoeka; Guxens, Mònica et al. (2018) Determinants of organophosphate pesticide exposure in pregnant women: A population-based cohort study in the Netherlands. Int J Hyg Environ Health 221:489-501
Beach, Tyler A; Groves, Angela M; Johnston, Carl J et al. (2018) Recurrent DNA damage is associated with persistent injury in progressive radiation-induced pulmonary fibrosis. Int J Radiat Biol 94:1104-1115
Morris-Schaffer, Keith; Sobolewski, Marissa; Welle, Kevin et al. (2018) Cognitive flexibility deficits in male mice exposed to neonatal hyperoxia followed by concentrated ambient ultrafine particles. Neurotoxicol Teratol 70:51-59
Santos, Susana; Eekhout, Iris; Voerman, Ellis et al. (2018) Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania. BMC Med 16:201
Huang, Li-Shan; Cory-Slechta, Deborah A; Cox, Christopher et al. (2018) Analysis of Nonlinear Associations between Prenatal Methylmercury Exposure from Fish Consumption and Neurodevelopmental Outcomes in the Seychelles Main Cohort at 17 Years. Stoch Environ Res Risk Assess 32:893-904

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