The purpose of the Facility is to provide statistical and data management services to EHSC faculty, postdoctoral fellows and graduate students for research projects directed toward generation of preliminary data. Support is also provided for Pilot Projects which may lead to submission of separate research proposals, preparation of grant proposals, and assistance with projects conducted by Toxicology graduate students and postdoctoral fellows, as well as support for projects with limited funding or for investigators who have experienced an interruption in funding. It is expected that individual grants originating from EHSC faculty will include support for any sustained statistical services. Support can include coverage of percentage of FTE of appropriate staff and faculty or via hourly billings. Specific support activities cover design, conduct and analysis of both laboratory and clinical studies as well as mathematical modeling of biological processes relevant to environmental studies. The Biostatistics Facility Core is located within the Department of Biostatistics and Computational Biology (DBCB) and draws upon the newly expanded resources of this department. Support services are provided under the direction of Dr. David Oakes and by Drs. Huang and Yakovlev, and are documented into a logbook.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES001247-32
Application #
7311780
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2006-04-01
Budget End
2007-03-31
Support Year
32
Fiscal Year
2006
Total Cost
$51,393
Indirect Cost
Name
University of Rochester
Department
Type
DUNS #
041294109
City
Rochester
State
NY
Country
United States
Zip Code
14627
Morris-Schaffer, Keith; Sobolewski, Marissa; Allen, Joshua L et al. (2018) Effect of neonatal hyperoxia followed by concentrated ambient ultrafine particle exposure on cumulative learning in C57Bl/6J mice. Neurotoxicology 67:234-244
Willis, Mary D; Jusko, Todd A; Halterman, Jill S et al. (2018) Unconventional natural gas development and pediatric asthma hospitalizations in Pennsylvania. Environ Res 166:402-408
Wahlberg, Karin; Love, Tanzy M; Pineda, Daniela et al. (2018) Maternal polymorphisms in glutathione-related genes are associated with maternal mercury concentrations and early child neurodevelopment in a population with a fish-rich diet. Environ Int 115:142-149
Cholette, Jill M; Pietropaoli, Anthony P; Henrichs, Kelly F et al. (2018) Elevated free hemoglobin and decreased haptoglobin levels are associated with adverse clinical outcomes, unfavorable physiologic measures, and altered inflammatory markers in pediatric cardiac surgery patients. Transfusion 58:1631-1639
Boule, Lisbeth A; Burke, Catherine G; Jin, Guang-Bi et al. (2018) Aryl hydrocarbon receptor signaling modulates antiviral immune responses: ligand metabolism rather than chemical source is the stronger predictor of outcome. Sci Rep 8:1826
Lacy, Shannon H; Woeller, Collynn F; Thatcher, Thomas H et al. (2018) Activated Human Lung Fibroblasts Produce Extracellular Vesicles with Anti-Fibrotic Prostaglandins. Am J Respir Cell Mol Biol :
Lacy, Shannon H; Epa, Amali P; Pollock, Stephen J et al. (2018) Activated human T lymphocytes inhibit TGF?-induced fibroblast to myofibroblast differentiation via prostaglandins D2 and E2. Am J Physiol Lung Cell Mol Physiol 314:L569-L582
Sobolewski, Marissa; Singh, Garima; Schneider, Jay S et al. (2018) Different Behavioral Experiences Produce Distinctive Parallel Changes in, and Correlate With, Frontal Cortex and Hippocampal Global Post-translational Histone Levels. Front Integr Neurosci 12:29
Caito, Samuel W; Jackson, Brian P; Punshon, Tracy et al. (2018) Editor's Highlight: Variation in Methylmercury Metabolism and Elimination Status in Humans Following Fish Consumption. Toxicol Sci 161:443-453
Begolly, Sage; Olschowka, John A; Love, Tanzy et al. (2018) Fractionation enhances acute oligodendrocyte progenitor cell radiation sensitivity and leads to long term depletion. Glia 66:846-861

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