The purpose of the Facility is to provide statistical and data management services to EHSC faculty, postdoctoral fellows and graduate students for research projects directed toward generation of preliminary data. Support is also provided for Pilot Projects which may lead to submission of separate research proposals, preparation of grant proposals, and assistance with projects conducted by Toxicology graduate students and postdoctoral fellows, as well as support for projects with limited funding or for investigators who have experienced an interruption in funding. It is expected that individual grants originating from EHSC faculty will include support for any sustained statistical services. Support can include coverage of percentage of FTE of appropriate staff and faculty or via hourly billings. Specific support activities cover design, conduct and analysis of both laboratory and clinical studies as well as mathematical modeling of biological processes relevant to environmental studies. The Biostatistics Facility Core is located within the Department of Biostatistics and Computational Biology (DBCB) and draws upon the newly expanded resources of this department. Support services are provided under the direction of Dr. David Oakes and by Drs. Huang and Yakovlev, and are documented into a logbook.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Center Core Grants (P30)
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Environmental Health Sciences Review Committee (EHS)
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University of Rochester
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Feiler, Marina Oktapodas; Patel, Deven; Li, Huiqi et al. (2018) The association between early-life relative telomere length and childhood neurodevelopment. Neurotoxicology 65:22-27
Duffney, Parker F; McCarthy, Claire E; Nogales, Aitor et al. (2018) Cigarette smoke dampens antiviral signaling in small airway epithelial cells by disrupting TLR3 cleavage. Am J Physiol Lung Cell Mol Physiol 314:L505-L513
Newman, Maureen R; Russell, Steven G; Schmitt, Christopher S et al. (2018) Multivalent Presentation of Peptide Targeting Groups Alters Polymer Biodistribution to Target Tissues. Biomacromolecules 19:71-84
Groves, Angela M; Johnston, Carl J; Williams, Jacqueline P et al. (2018) Role of Infiltrating Monocytes in the Development of Radiation-Induced Pulmonary Fibrosis. Radiat Res 189:300-311
Sobolewski, Marissa; Conrad, Katherine; Marvin, Elena et al. (2018) Endocrine active metals, prenatal stress and enhanced neurobehavioral disruption. Horm Behav 101:36-49
Klocke, Carolyn; Allen, Joshua L; Sobolewski, Marissa et al. (2018) Exposure to fine and ultrafine particulate matter during gestation alters postnatal oligodendrocyte maturation, proliferation capacity, and myelination. Neurotoxicology 65:196-206
McSorley, Emeir M; Yeates, Alison J; Mulhern, Maria S et al. (2018) Associations of maternal immune response with MeHg exposure at 28 weeks' gestation in the Seychelles Child Development Study. Am J Reprod Immunol 80:e13046
Duffney, Parker F; Falsetta, Megan L; Rackow, Ashley R et al. (2018) Key roles for lipid mediators in the adaptive immune response. J Clin Invest 128:2724-2731
Morris-Schaffer, Keith; Sobolewski, Marissa; Allen, Joshua L et al. (2018) Effect of neonatal hyperoxia followed by concentrated ambient ultrafine particle exposure on cumulative learning in C57Bl/6J mice. Neurotoxicology 67:234-244
Willis, Mary D; Jusko, Todd A; Halterman, Jill S et al. (2018) Unconventional natural gas development and pediatric asthma hospitalizations in Pennsylvania. Environ Res 166:402-408

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