Abstract

The primary function of the Morphology Module is to make available tovision researchers both the instruments and expertise required to perform microscopic analyses of ocularspecimens, subcellular fractions, or cultured cells. A centralized facility is essential since virtually all the labscientists in our group must examine cell or tissue structure for some aspects of their work, but each individualcannot justify or support a fully-equipped microscopy lab (including an electron microscope), or the ongoingsalaries of skilled microscopy technicians. The Module prepares specimens for light and electron microscopy,including special stains and histochemical reactions, and for immunofluorescence microscopy, confocal imagingand in situ hybridization.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
2P30EY001931-31
Application #
7286509
Study Section
Special Emphasis Panel (ZEY1-VSN (03))
Project Start
2007-04-01
Project End
2012-03-31
Budget Start
2007-04-01
Budget End
2008-03-31
Support Year
31
Fiscal Year
2007
Total Cost
$73,726
Indirect Cost

  Institution

Name
Medical College of Wisconsin
Department
Type
DUNS #
937639060
City
Milwaukee
State
WI
Country
United States
Zip Code
53226

  Publications

Strampe, Margaret R; Huckenpahler, Alison L; Higgins, Brian P et al. (2018) Intraobserver Repeatability and Interobserver Reproducibility of Ellipsoid Zone Measurements in Retinitis Pigmentosa. Transl Vis Sci Technol 7:13
Pinhas, Alexander; Linderman, Rachel; Mo, Shelley et al. (2018) A method for age-matched OCT angiography deviation mapping in the assessment of disease- related changes to the radial peripapillary capillaries. PLoS One 13:e0197062
Hirji, Nashila; Georgiou, Michalis; Kalitzeos, Angelos et al. (2018) Longitudinal Assessment of Retinal Structure in Achromatopsia Patients With Long-Term Follow-up. Invest Ophthalmol Vis Sci 59:5735-5744
Krawitz, Brian D; Phillips, Erika; Bavier, Richard D et al. (2018) Parafoveal Nonperfusion Analysis in Diabetic Retinopathy Using Optical Coherence Tomography Angiography. Transl Vis Sci Technol 7:4
Sajdak, Benjamin S; Bell, Brent A; Lewis, Tylor R et al. (2018) Assessment of Outer Retinal Remodeling in the Hibernating 13-Lined Ground Squirrel. Invest Ophthalmol Vis Sci 59:2538-2547
Datta, Shyamtanu; Renwick, Marian; Chau, Viet Q et al. (2018) A Destabilizing Domain Allows for Fast, Noninvasive, Conditional Control of Protein Abundance in the Mouse Eye - Implications for Ocular Gene Therapy. Invest Ophthalmol Vis Sci 59:4909-4920
Mainali, Laxman; O'Brien, William J; Subczynski, Witold K (2018) Detection of cholesterol bilayer domains in intact biological membranes: Methodology development and its application to studies of eye lens fiber cell plasma membranes. Exp Eye Res 178:72-81
Hendee, Kathryn E; Sorokina, Elena A; Muheisen, Sanaa S et al. (2018) PITX2 deficiency and associated human disease: insights from the zebrafish model. Hum Mol Genet 27:1675-1695
Lapierre-Landry, Maryse; Huckenpahler, Alison L; Link, Brian A et al. (2018) Imaging Melanin Distribution in the Zebrafish Retina Using Photothermal Optical Coherence Tomography. Transl Vis Sci Technol 7:4
Patterson, Emily J; Kalitzeos, Angelos; Kasilian, Melissa et al. (2018) Residual Cone Structure in Patients With X-Linked Cone Opsin Mutations. Invest Ophthalmol Vis Sci 59:4238-4248

Showing the most recent 10 out of 517 publications